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The post COVID-19 healthcare landscape and the use of long-acting injectable antipsychotics for individuals with schizophrenia and bipolar I disorder: the importance of an integrated collaborative-care approach.
BMC Psychiatry
January 2022
The Zucker Hillside Hospital, Department of Psychiatry Research, Northwell Health, 75-59 263rd Street, Glen Oaks, NY, 11004, USA.
Background: Long-acting injectable antipsychotics (LAIs) are an essential maintenance treatment option for individuals with schizophrenia or bipolar I disorder (BP-I). This report summarizes a roundtable discussion on the impact of COVID-19 on the mental healthcare landscape and use of LAIs for individuals with schizophrenia or BP-I.
Methods: Ten experts and stakeholders from diverse fields of healthcare participated in a roundtable discussion on the impact of the COVID-19 pandemic, treatment challenges, and gaps in healthcare for individuals with schizophrenia or BP-I, informed by a literature search.
Quantitative assessment of environmental impact of biologics manufacturing using process mass intensity analysis.
Biotechnol Prog
November 2018
Upstream Process Development and Engineering, Biologics Process Development and Clinical Manufacturing, Merck & Co., Inc. (USA), 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
Process mass intensity (PMI) is a benchmarking metric to evaluate the efficiency of a manufacturing process, which is indicative of the environmental impact of the process. Although this metric is commonly applied for small molecule manufacturing processes, it is less commonly applied to biologics. In this study, an Excel based tool developed by the ACS GCI Pharmaceutical Roundtable was used to calculate PMI of different manufacturing processes for a monoclonal antibody (mAb).
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