Unlabelled: The internal hydrostatic pressure (IHP) of the intervertebral disc is the functional and physiological basis of the spine. Disc bulging is a direct effect of increased IHP and can be used to evaluate the IHP without destroying the structure of the disc. Disc tissue engineering is a developing field but more data on the properties of normal discs are required for evaluation of possible graft materials. However, very little data is available concerning bulge distribution along the normal disc surface under creep.
Methods: Fifteen motion segment specimens of ovine IVD were used to analyze axial creep, and disc bulging deformations of 5 markers on the surface were measured and analyzed.
Findings: The maximum radial bulging rate was 2.78%± 1.09% and the position at which the maximum radial deformation occurred was found to be below the midline of the disc during all levels of loading. The results showed that deformations occurred in the order vertical, radial, circumferential.
Interpretation: Disc bulging during creep is a very important biomechanical response, affecting spinal functions. The deformation regularities of the disc surface were identified and may help supply important basic data for disc tissue engineering.
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http://dx.doi.org/10.3233/BME-130799 | DOI Listing |
FASEB J
January 2025
HSS Research Institute, Hospital for Special Surgery, New York, New York, USA.
Aging is a risk factor for several chronic conditions, including intervertebral disc degeneration and associated back pain. Disc pathologies include loss of reticular-shaped nucleus pulposus cells, disorganization of annulus fibrosus lamellae, reduced disc height, and increased disc bulging. Sonic hedgehog, cytokeratin 19, and extracellular matrix proteins are markers of healthy disc.
View Article and Find Full Text PDFAm J Sports Med
January 2025
Department of Radiology, Balgrist University Hospital, Faculty of Medicine, University of Zurich, Zurich, Switzerland.
Background: Overuse-related intersegmental abnormalities in the spine of competitive alpine skiers are common findings. However, longitudinal changes in intersegmental abnormalities and symptoms throughout adolescence have not been assessed.
Purpose: To longitudinally assess and compare overuse-related spinal intersegmental abnormalities in adolescent competitive alpine skiers over 48 months and to compare magnetic resonance imaging (MRI) findings in asymptomatic and symptomatic skiers.
Cureus
November 2024
Spinal Surgery, Kameda Medical Center, Chiba, JPN.
Discogenic low back pain (DLBP) is difficult to diagnose. We performed full endoscopic spinal surgery (FESS) with thermal annuloplasty for DLBP and achieved good results. Here, we report a case in which thermal annuloplasty resulted in good outcomes for refractory DLBP accompanied by a residual high-intensity zone (HIZ) after full endoscopic discectomy (FED).
View Article and Find Full Text PDFWorld J Clin Cases
December 2024
Department of Physical Medicine and Rehabilitation, Dongnam Institute of Radiological and Medical Sciences, Busan 46033, South Korea.
Ann Med Surg (Lond)
December 2024
Taleghani Pediatric Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
Introduction And Importance: Cystic fibrosis (CF) is a widespread life-shortening recessive genetic disease and can present with sinus mucocele. Sinus mucocele is a rare condition, with limited prevalence data on unilateral proptosis.
Case Presentation: The authors present a case of a 19-month-old boy with CF who experienced worsening proptosis and exotropia in his right eye.
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