The cerebellum, which is important for movement control and planning, is often affected by many neurological conditions. Until now there has been limited information regarding how the function of the cerebellum impacts driving ability. This study used fMRI with an integrated virtual reality driving simulator to determine which aspects of driving performance are related to the cerebellum in healthy drivers (Experiment 1). It also investigated drivers with focal cerebellar lesions to identify how damage to this brain region impairs driving abilities. The results showed that cerebellar functioning is responsible for motor-speed coordination and complex temporal-motor integration necessary to execute driving behaviours. As predicted, drivers with cerebellar damage, showed significantly compromised speed control during basic driving conditions, whereas their ability to perform during interactive driving situations was preserved. New insights into neural mechanisms and brain plasticity regarding driving behaviour are discussed. Strategies in assessing and rehabilitating drivers with related neurological conditions are provided.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.neulet.2013.10.065 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Marine and atmospheric transport modeling supporting nuclear preparedness in Norway: Recent achievements and remaining challenges.
Sci Total Environ
January 2025
Center for Environmental Radioactivity (CERAD) CoE, Norwegian University of Life Sciences, P.O. Box 5003, N-1432 Ås, Norway; Faculty of Environmental Sciences and Natural Resource Management, Norwegian University of Life Sciences (NMBU), P.O.Box 5003, NO-1432 Ås, Norway.
Numerical transport models are important tools for nuclear emergency decision makers in that they rapidly provide early predictions of dispersion of released radionuclides, which is key information to determine adequate emergency protective measures. They can also help us understand and describe environmental processes and can give a comprehensive assessment of transport and transfer of radionuclides in the environment. Transport of radionuclides in air and ocean is affected by a number of different physico-chemical processes.
View Article and Find Full Text PDFEffects of fire recurrence and severity on Mediterranean vegetation dynamics: Implications for structure and composition in southern Spain.
Sci Total Environ
January 2025
Forest Fire Laboratory (LABIF), Forestry Engineering Department, University of Cordoba, 14071 Cordoba, Spain. Electronic address:
Most Mediterranean ecosystems have been profoundly shaped by wildfires, driving the evolution of plant species. Through photo interpretation and field inventories, this research assessed vegetation dynamics from 1984 to 2021, examining how fire severity and recurrence, key fire regime variables, influenced changes in structure and woody species diversity. Using two burn scars (1988 and 2006), we identified four scenarios dominated by Pinus pinea tree species: control (unburned), areas burned once (either in 1988 or 2006), and twice (in both 1988 and 2006).
View Article and Find Full Text PDFJMJD8 regulates adipocyte hypertrophy through the interaction with Perilipin 2.
Diabetes
January 2025
Nutritional Sciences and Toxicology Department, University of California Berkeley, Berkeley, CA 94720, US.
Adipocyte hypertrophy significantly contributes to insulin resistance and metabolic dysfunction. Our previous research established JMJD8 as a mediator of insulin resistance, noting its role in promoting adipocyte hypertrophy within an autonomous adipocyte context. Nevertheless, the precise mechanisms underlying this phenomenon remained elusive.
View Article and Find Full Text PDFRefining fine-mapping: Effect sizes and regional heritability.
PLoS Genet
January 2025
Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
Recent statistical approaches have shown that the set of all available genetic variants explains considerably more phenotypic variance of complex traits and diseases than the individual variants that are robustly associated with these phenotypes. However, rapidly increasing sample sizes constantly improve detection and prioritization of individual variants driving the associations between genomic regions and phenotypes. Therefore, it is useful to routinely estimate how much phenotypic variance the detected variants explain for each region by taking into account the correlation structure of variants and the uncertainty in their causal status.
View Article and Find Full Text PDFStress drives a switch in sex preference.
Science
January 2025
Salk Institute for Biological Studies, La Jolla, CA, USA.
Distinct brain circuits control sex preferences in mice.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!