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http://dx.doi.org/10.1016/j.sleep.2013.06.022 | DOI Listing |
Surg Neurol Int
October 2022
Internal Medicine, Fundacion Jimenez Diaz University Hospital, Madrid, Spain.
Background: Whipple disease (WD) is an infection caused by , which might present in three different forms: classical, localized, and isolated in the central nervous system (CNS).
Methods: We report the result of a systematic review of the literature on WD unusually presenting with exclusively neurological symptoms, including two previously unpublished cases. A description of two cases with isolated CNS WD was performed, as well as a literature search in , and .
Lancet Rheumatol
July 2020
Cochin Hospital, University Paris Descartes, Assistance Publique-Hôpitaux de Paris, Paris, France. Electronic address:
Indian J Psychol Med
January 2018
Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Introduction: Whipple's disease (WD) is a very rare systemic disease caused by the gram-positive bacillus Tropherymawhippleii 1st described in the year 1907. It is a disease with multisystem involvement and high degree of suspicion is needed for diagnosis. However the classical (OMM)oculomasticatory (OFMM)oculofacial-skeletal myorhythmia clubbed with dementia, head ache and other neurologic features should deserve an attempt to confirm whenever possible and therapeutic trial as it is one of the treatable dementias.
View Article and Find Full Text PDFFront Neurol
July 2017
Daroff-Dell'Osso Ocular Motility Laboratory, Cleveland VA Medical Center, Cleveland, VA, United States.
Whipple's disease, a rare systemic infectious disorder, is complicated by the involvement of the central nervous system in about 5% of cases. Oscillations of the eyes and the jaw, called oculo-masticatory myorhythmia, are pathognomonic of the central nervous system involvement but are often absent. Typical manifestations of the central nervous system Whipple's disease are cognitive impairment, parkinsonism mimicking progressive supranuclear palsy with vertical saccade slowing, and up-gaze range limitation.
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