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| http://dx.doi.org/10.1371/journal.pntd.0002321 | DOI Listing |
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Lifespan Extension and Motor Function Improvement Effects of Whale Meat Extract in .
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Department of Functional Morphology, Shonan University of Medical Sciences, 16-48 Kamishinano, Totsuka-ku, Yokohama 244-0806, Kanagawa, Japan.
The average life expectancy is increasing worldwide, but the same cannot be said for a healthy life expectancy (defined as the period during which a person can live a healthy and independent life). Therefore, a major challenge is how to extend healthy life expectancy. One option is to reduce age-related muscle atrophy (sarcopenia) and cognitive decline.
View Article and Find Full Text PDFBrain MRI findings and thoracic CT findings in a dog with hemiparesis and acutely diminished Von-Willebrand factor levels through Angiostrongylus vasorum infection.
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IVC Evidensia GmbH, Hofheim Animal Hospital, Hofheim am Taunus, Germany.
A 2-year-old intact male Airedale Terrier was presented with a sudden onset of neurological signs, manifesting as hemiparesis, which were neuroanatomically localized to the brain. Initial bloodwork conducted by the local veterinarian indicated decreased levels of von Willebrand factor, and further examination showed an extended buccal mucosal bleeding time. MRI revealed a substantial hemorrhage within the right parietal lobe, while CT exhibited a mixed pulmonary pattern with unstructured interstitial, peribronchial, and alveolar components, presumably associated with larval migration and pulmonary microhemorrhages.
View Article and Find Full Text PDFStructural dynamics and binding of Caenorhabditis elegans lifespan-extending lipid binding protein-3 to polyunsaturated fatty acids.
Protein Sci
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Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.
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View Article and Find Full Text PDFDietary state and impact of DMSO on Caenorhabditis elegans aging: Insights from healthspan analysis.
Biochem Biophys Res Commun
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Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-Honmachi, Chuo-ku, Kumamoto, 862-0973, Japan; Global Center for Natural Resources Sciences, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-Honmachi, Chuo-ku, Kumamoto, 862-0973, Japan. Electronic address:
Article Synopsis
- C. elegans is a key model organism used in various biological studies due to its short lifespan, fast reproduction, and genetic similarities to mammals, particularly useful in aging research.
- Recent findings demonstrate that C. elegans fed heat-killed or freeze-dried E. coli show better lifespan and healthspan compared to those fed live bacteria, indicating the importance of food source conditions.
- The study also reveals that a 0.1% DMSO treatment negatively affects lifespan and healthspan in C. elegans when fed dead bacteria, emphasizing the need to consider experimental conditions in longevity research.
Characterisation and serodiagnostic evaluation of a recombinant 22.6-kDa tegument protein of .
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Kerala Veterinary and Animal Sciences University (KVASU), Pookode, Wayanad, Kerala, India.
Schistosomosis in animals due to significantly burdens India's livestock economy because of high prevalence and morbidity and is mostly underdiagnosed from the lack of sensitive tools for field-level detection. This study aimed to clone, express the 22.6-kDa tegument protein of (rSs22.
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