Several novel chiral N-heterocyclic carbene and phosphine ligands were prepared from (S)-BINOL. Moreover, their ligated Au complexes were also successfully synthesized and characterized by X-ray crystal diffraction. A weak gold-π interaction between the Au atom and the aromatic ring in these gold complexes was identified. Furthermore, we confirmed the formation of a pair of diastereomeric isomers in NHC gold complexes bearing an axially chiral binaphthyl moiety derived from the hindered rotation around C-C and C-N bonds. In the asymmetric intramolecular hydroamination reaction most of these chiral Au(I) complexes showed good catalytic activities towards olefins tethered with a NHTs functional group to give the corresponding product in moderate yields and up to 29% ee.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817475 | PMC |
| http://dx.doi.org/10.3762/bjoc.9.261 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background/objectives: Bone marrow (BM) adipocytes are critical in progressing solid tumor metastases and hematological malignancies across pediatric to aging populations. Single-point biopsies remain the gold standard for monitoring BM diseases, including hematologic malignancies, but are limited in capturing the full complexity of loco-regional and global BM microenvironments. Non-invasive imaging techniques like Magnetic Resonance Imaging (MRI), could offer valuable alternatives for real-time evaluation of BM diseases in both preclinical translational and clinical studies.
View Article and Find Full Text PDFCase report: Diagnostic challenges of papulonodular mucinosis in a 67-year-old female.
SAGE Open Med Case Rep
January 2025
Division of Dermatology, University of Saskatchewan College of Medicine, Saskatoon, SK, Canada.
Papulonodular mucinosis is a rare dermatological condition characterized by mucin deposition in the dermis, leading to the formation of papules and nodules that can occur with, or antedate, autoimmune connective tissue diseases. This case report presents a 67-year-old female with a chronic history of cutaneous mucinosis, which posed significant diagnostic challenges. Despite various treatments and extensive diagnostic workup, her condition evolved, highlighting the difficulties in diagnosing papulonodular mucinosis, especially in the absence of systemic lupus erythematosus and antinuclear antibody positivity.
View Article and Find Full Text PDFLuminescent cyclometalated gold(iii) complexes covalently linked to metal-organic frameworks for heterogeneous photocatalysis.
Chem Sci
December 2024
Department of Chemistry, State Key Laboratory of Synthetic Chemistry, The University of Hong Kong Pokfulam Road Hong Kong P. R. China
Phosphorescent gold(iii) complexes possess long-lived emissive excited states, making them ideal for use as molecular sensors and photosensitizers for organic transformations. Literature reports indicate that gold(iii) emitters exhibit good catalytic activity in homogeneous photochemical reactions. Heterogeneous metal-organic framework (MOF)-supported gold(iii) photocatalysts are considered to show high recyclability in photochemical reactions and potentially provide new selectivities.
View Article and Find Full Text PDFElectrochemical Controlling of Double Microgel Layer Formation on an Electrode Surface via an Electrosensitive Inclusion Complex.
ACS Mater Au
January 2025
Faculty of Chemistry, University of Warsaw, 1 Ludwika Pasteura Str., PL 02-093 Warsaw, Poland.
In this study, we demonstrate the formation of a self-assembled microgel double layer on an electrode surface, utilizing the ability to form electro-responsive, reversible inclusion complexes between microgels modified with ferrocene and β-cyclodextrin in these systems. The bottom layer was based on microgels containing ferrocene moieties and derivatives of cysteine. The presence of the amino acid derivative enabled the formation of the well-packed monolayer on the gold surface through chemisorption, while ferrocene was responsible for electroactivity.
View Article and Find Full Text PDFA label-free electrochemical biosensor based on graphene quantum dots-nanoporous gold nanocomposite for highly sensitive detection of glioma cell.
Anal Chim Acta
February 2025
School of Life Sciences, The Second Affiliated Hospital, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, PR China. Electronic address:
Background: Glioma accounts for 80 % of all malignant primary brain tumors with a high mortality rate. Histopathological examination is the current diagnostic methods for glioma, but its invasive surgical interventions can cause cerebral edema or impair neural functioning. Liquid biopsy proves to be an efficient method for glioma detection.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!