AI Article Synopsis
- Oxabicyclic alkenes react with electron-deficient terminal alkynes in mild conditions using a gold catalyst to yield addition products in moderate yields.
- When alkynyl esters are the substrate, the resulting products are (Z)-acrylate derivatives.
- Using but-3-yn-2-one leads to an addition product with an (E)-configuration, and the text also discusses the mechanism behind these reactions.
Article Abstract
Oxabicyclic alkenes can react with electron-deficient terminal alkynes in the presence of a gold catalyst under mild conditions, affording the corresponding addition products in moderate yields. When using alkynyl esters as substrates, the (Z)-acrylate derivatives are obtained. Using but-3-yn-2-one (ethynyl ketone) as a substrate, the corresponding addition product is obtained with (E)-configuration. The proposed mechanism of these reactions is also discussed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817539 | PMC |
| http://dx.doi.org/10.3762/bjoc.9.233 | DOI Listing |
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