Sodium valproate-induced enuresis in a pediatric bipolar patient.

Neuropsychiatr Dis Treat

Department of Pediatric and Geriatric Psychiatry, Fuzhou Neuropsychiatric Hospital, Fuzhou, Fujian, People's Republic of China.

Published: November 2013

Sodium valproate (SV) is effective and well tolerated for the treatment of epilepsy and mood disorders. There are several cases of SV-induced enuresis noted in epileptic patients. No alternative medication has been suggested to manage this problem. We present the first case of a pediatric bipolar patient who developed diurnal and nocturnal enuresis during SV therapy. Clinicians should be aware of this side effect, as it has not been reported in nonepileptic patients, and it may be detrimental to treatment adherence.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817031PMC
http://dx.doi.org/10.2147/NDT.S53388DOI Listing

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