This is the fourth installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at http://www.aseronline.org/curriculum/toc.htm .
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Depression-related innate immune genes and pan-cancer gene analysis and validation.
Front Genet
January 2025
Department of Pharmacology, The Key Laboratory of Neural and Vascular Biology, The Key Laboratory of New Drug Pharmacology and Toxicology, Ministry of Education, Collaborative Innovation Center of Hebei Province for Mechanism, Diagnosis and Treatment of Neuropsychiatric Diseases, Hebei Medical University, Shijiazhuang, Hebei, China.
Background: Depression, a prevalent chronic mental disorder, presents complexities and treatment challenges that drive researchers to seek new, precise therapeutic targets. Additionally, the potential connection between depression and cancer has garnered significant attention.
Methods: This study analyzed depression-related gene expression data from the GEO database.
Integrating e-learning into the educational framework for undergraduate medical training: a Nigerian survey on trainers´ perception and readiness.
Pan Afr Med J
October 2024
Department of Paediatrics, Olabisi Onabanjo University, Ago-Iwoye, Ogun State, Nigeria.
Introduction: given the significant disruption in educational activities during the COVID-19 pandemic and the uncertainties about the post-pandemic future, coupled with increasing demand for the healthcare workforce, e-learning may bridge the gap in training medical students. It was imperative to survey the perception and readiness of the trainers on the use of e-learning for undergraduate medical training in Nigeria.
Methods: this cross-sectional study was conducted among teachers of medical students in Nigeria.
Correction: Three-dimensional TiNbO anchored on carbon nanofiber core-shell arrays as an anode for high-rate lithium ion storage.
RSC Adv
January 2025
Key Laboratory of Engineering Dielectric and Applications (Ministry of Education), School of Materials Science and Engineering, Harbin University of Science and Technology Harbin 150080 P. R. China
[This corrects the article DOI: 10.1039/C9RA10485B.].
View Article and Find Full Text PDFExtracellular domain of TREM2 possess two distinct ligand recognition sites: Insights from machine-learning guided docking and all-atoms molecular dynamics simulations.
Heliyon
January 2025
Department of Bioinformatics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India.
The myeloid-specific triggering receptors expressed on myeloid cells 2 (TREM2) is a group of class I receptors expressed in brain microglia plays a decisive role in neurodegenerative diseases such as Alzheimer's disease (AD) and Nasu Hakola disease (NHD). The extracellular domain (ECD) of TREM2 interacts with a wide-range of ligands, yet the molecular mechanism underlying recognition of such ligands to this class I receptor remains underexplored. Herein, we undertook a systematic investigation for exploring the mode of ligand recognition in immunoglobulin-like ectodomain by employing both knowledge-based and machine-learning guided molecular docking approach followed by the state-of-the-art all atoms molecular dynamics (MD) simulations.
View Article and Find Full Text PDFTop 75 most-cited articles in hand microsurgery: A bibliometric and visualised analysis.
J Hand Microsurg
March 2025
Division of Surgery and Interventional Science, University College London, London, United Kingdom.
Introduction: Hand microsurgery is an important advancement of the speciality that has improved outcomes in hand trauma and hand surgical conditions. This bibliometric analysis aims to identify the 75 most cited hand microsurgery articles and explore their relevance to contemporary practice.
Methods: The Web of Science core collection database was used to screen and identify the top 75 most-cited articles relevant to hand microsurgery.
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