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Nitrates administered by spray versus tablet: comparison of coronary vasodilation on CT angiography.
Eur Radiol
January 2021
Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi, 15355, South Korea.
Objectives: To compare the coronary vasodilation effects of spray with those induced by tablet administration in coronary CT angiography (CCTA).
Methods: A total of 2024 patients who underwent CCTA were identified for this retrospective study, including 828 patients with spray (spray group) and 1169 with tablets (tablet group). Of these, 93 patients underwent CCTA at least twice using both spray and tablets.
Comparison of vaginal misoprostol, laminaria, and isosorbide dinitrate on cervical preparation and labor duration of term parturient: a randomized double-blind clinical trial.
Electron Physician
May 2018
M.Sc. of Nursing, Instructor, Department of Operating Room, School of Paramedics, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Background: Cervical ripening plays an important role in successful labor induction.
Objective: This study aimed to compare the effects of misoprostol, laminaria tent, and isosorbide dinitrate (ISDN) on cervical ripening.
Methods: This double-blind three-armed clinical trial was conducted at Shahidan Mombini Teaching Hospital in Sabzevar, Iran, in 2016 on 96 singleton term pregnant women.
Isoprenaline versus nitroglycerine in head-up tilt test.
Indian Heart J
October 2017
Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Cardiology, B.G. Road, Bangalore 560069, Karnataka, India. Electronic address:
Background: HUTT test is used in evaluation of syncope. Isoprenaline and isosorbide dinitrate are used to increase the sensitivity of the test. These drugs act by different mechanisms.
View Article and Find Full Text PDFNitric oxide donors for cervical ripening and induction of labour.
Cochrane Database Syst Rev
December 2016
Department of Obstetrics and Gynaecology, Brighton and Sussex University Hospitals NHS Trust, Eastern Road, Brighton, UK, BN2 5BE.
Background: Sometimes it is necessary to bring on labour artificially because of safety concerns for the mother or baby. This review is one of a series of reviews of methods of labour induction using a standardised protocol.
Objectives: To determine the effects of NO donors (isosorbide mononitrate (ISMN), isosorbide dinitrate (ISDN), nitroglycerin and sodium nitroprusside) for third trimester cervical ripening or induction of labour, in comparison with placebo or no treatment or other treatments from a predefined hierarchy.
The "induced hyperactivity" test for the de-risking of potential off-target activity of antihypertensive drugs.
J Pharmacol Toxicol Methods
May 2017
BPH-DD-ED-TOX, Safety Pharmacology, Bayer Pharma AG, Aprather Weg 18a, D-42096 Wuppertal, Germany.
Introduction: Compound X is a new proprietary antihypertensive agent that induces its pharmacodynamic effect at an approximate plasma Cmax.u of 0.6nmol/L (rat hypertension model).
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