A major incident involving phthalates-contaminated foodstuffs occurred in Taiwan in May 2011, leading to the quick removal of tainted food items from store shelves. We investigated changes in urinary oxidative di(2-ethylhexyl)phthalate (DEHP) metabolites, our proxy for exposure to DEHP-tainted foodstuffs in children ≤10 years, during the six months following withdrawal of the tainted food. Our hospital screened 60 possibly exposed children between May and June 2011. The children's food intake information was collected, and they were administered one-spot urine samples at baseline and at the two and six month follow-ups. All three samples were measured for four oxidative DEHP metabolites, mono-(2-ethyl-5-hydroxyhexyl) phthalate (5OH-MEHP), mono-(2-ethyl-5-oxohexyl) phthalate (5oxo-MEHP), mono-(2-ethyl-5-carboxypentyl) phthalate (5cx-MEPP), and mono-(2-carboxymethylhexyl) phthalate (2cx-MMHP) by triple quadrupole liquid chromatography tandem mass spectrometry. Fifty-two children had been exposed. After excluding those without a full set of urine samples or adequate food intake information, 23 exposed children were studied. We found significantly positive correlations between DEHP daily intake and urinary 5OH-MEHP, 5oxo-MEHP, and 5cx-MEPP (p < 0.05). At the six month follow-up, all four metabolite concentrations had significantly decreased compared to the baseline. In conclusion, urinary DEHP metabolites decreased progressively in children after tainted food withdrawal, indicating that the main sources of phthalate contamination for children had been successfully controlled.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/es403141u | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bottle Aging of Smoke-Affected Wines: Changes in Smoke Flavor and Chemical Composition.
J Agric Food Chem
January 2025
The Australian Wine Research Institute, P.O. Box 46, Glenside (Adelaide), SA 5065, Australia.
Winegrapes exposed to environmental wildfire smoke during ripening can be identified through analysis of volatile phenols and phenolic glycosides. While elevated concentrations of these smoke marker compounds in grapes have been shown to be predictive of composition and smoke flavor in young wines, recent research has demonstrated that not every wine produced from smoke-exposed grapes will inevitably have discernible smoke flavor when assessed as young wine 6 weeks after bottling. This is supported by anecdotal reports from wine producers that wines that do not appear noticeably smoky when young become noticeably smoky during aging.
View Article and Find Full Text PDFUnregulated male sexual enhancement treatments: Perils and pitfalls for patients and providers.
J Am Assoc Nurse Pract
January 2025
Center for AIDS Preventions Studies (CAPS), University of California San Francisco, San Francisco, California.
As the demand for "quick-fixes" and instant gratification intensifies among consumers of the US health care delivery system, health care providers remain essential to ensuring patients receive safe, evidenced-based care. Erectile dysfunction is a common health condition affecting as many as 42% of US men. As such, it is unsurprising that American health care consumers affected by erectile dysfunction (ED) may be tempted by "quick fixes" to ameliorate their symptoms-particularly if such fixes are perceived to be less embarrassing, more accessible, and/or more affordable.
View Article and Find Full Text PDFA comprehensive review of paratuberculosis in animals and its implications for public health.
Open Vet J
November 2024
Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Paratuberculosis is an infectious disease caused by subspecies (MAP). Typically, ruminant animals including cattle, buffalo, goats, and sheep are infected with MAP. Animals get infected with MAP in a number of ways, such as by eating or drinking contaminated food or water, or by nursing from an infected mother who may have contaminated teats or directly shed the organism in milk or colostrum.
View Article and Find Full Text PDFAnalysis of children's kidney stones and comparison to canine kidney stones: Both resulting from ingesting adulterated food products.
Toxicol Appl Pharmacol
December 2024
Hanford Mission Integration Solutions, Richland, WA, USA. Electronic address:
Article Synopsis
- Kidney stones caused by melamine contamination were first seen in dogs and cats between 2004 and 2007, with specific analysis revealing a mix of melamine and cyanuric acid in the stones.
- Researchers noted a unique green coloration in canine stones due to biliverdin, while similar studies on human kidney stones found melamine and uric acid but no green color.
- The findings highlight the need for strict monitoring of food additives to protect both animals and humans from harmful contamination.
Consumer animal welfare and healthy perception of fresh sausages' fiber fat replaced and elaborated with meat from non-castrated male pigs.
Food Sci Nutr
September 2024
Department of Food Science and Technology, Veterinary Faculty University of Murcia Murcia Spain.
Although replacement of fat with fiber is a good strategy to avoid boar taint on high-fat content products, as sausages, the final purchase intention is related to other external factors such as welfare and healthiness. So, the aim of this study was to evaluate the consumers' perception of sausages with fat replaced by fiber, elaborated with meat from non-castrated male pigs, and to determine the influence of the consumers' habits and demographic parameters on their beliefs related to pig castration. An online survey was carried out.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!