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Tularemia is a re-emerging zoonosis in many endemic countries. It is caused by , a gram-negative bacterium and biological threat agent. Humans are infected from the wild animal reservoir, the environmental reservoir or by the bite of arthropod vectors.

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Article Synopsis
  • Acute focal lymphadenitis in humans can occasionally be caused by zoonotic pathogens, which are transmitted without direct contact with infected animals, often via vectors.
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Tularemia caused by Gram-negative, coccobacillus bacterium, is a highly infectious zoonotic disease. Human cases have been reported mainly from the United States, Nordic countries like Sweden and Finland, and some European and Asian countries. Naturally, the disease occurs in several vertebrates, particularly lagomorphs.

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Tularemia is increasing in Austria. We report Francisella tularensis subspecies holarctica isolated from 3 patients who had been bitten by arthropods. Next-generation sequencing showed substantial isolate similarity.

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Background: Understanding the microbiota of disease vectors can help for developing new strategies to prevent the transmission of vector pathogens. is one of the most notorious tick vectors with increasing importance in Iran and other parts of the world while there is limited data on its microbiota. This study aimed to use metagenomics for identifying the tick's microbiota of Iran.

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