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Imaging of RNAs in live cells with spectrally diverse small molecule fluorophores. | LitMetric

Imaging of RNAs in live cells with spectrally diverse small molecule fluorophores.

Analyst

Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Dr., Madison, WI 53706, USA.

Published: January 2014

AI Article Synopsis

Article Abstract

We have developed new protein-based tags for use in imaging of RNAs in living cells. These tags are based on the MS2 phage coat protein fused to either E. coli dihydrofolate reductase or the SNAP tag. Labeled RNAs can be visualized with fluorophores spanning the visible spectra range.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873762PMC
http://dx.doi.org/10.1039/c3an01550eDOI Listing

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