Robotic rehabilitation is an effective platform for sensorimotor training after neurological injuries. In this paper, an adaptive controller is developed and implemented for the RiceWrist, a serial-in-parallel robot mechanism for upper extremity robotic rehabilitation. The model-based adaptive controller implementation requires a closed form dynamic model, valid for a restricted domain of generalized coordinates. We have used an existing method to define this domain and verify that the domain is widely within the range of admissible tasks required for the considered application (movements-based wrist and forearm rehabilitation). Simulation and experimental results that compare the performance of the adaptive controller to a proportional-derivative controller show that the trajectory tracking performance of the adaptive controller is better compared to the performance of a PD controller using the same values of feed-back gains. Further, comparable absolute error performance is obtained with the adaptive controller for feedback gains nearly one third that required for the PD controller. With the lower gains used in the adaptive controller, good tracking performance is achieved with a more compliant controller that will allow the subject to indicate their ability to independently initiate and maintain movement during a rehabilitation session.
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http://dx.doi.org/10.1109/ICORR.2013.6650412 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
Textile and Clothing College, Qingdao University, Qingdao 266071, China.
Fiber-based strain sensors, as wearable integrated devices, have shown substantial promise in health monitoring. However, current sensors suffer from limited tunability in sensing performance, constraining their adaptability to diverse human motions. Drawing inspiration from the structure of the spiranthes sinensis, this study introduces a unique textile wrapping technique to coil flexible silver (Ag) yarn around the surface of multifilament elastic polyurethane (PU), thereby constructing a helical structure fiber-based strain sensor.
View Article and Find Full Text PDFDisabil Rehabil
January 2025
Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.
Purpose: 1) To identify outcome measures used in support programs designed to enhance functioning in autistic children and adolescents, and 2) To map the content of these measures to the domains of the International Classification of Functioning, Disability and Health (ICF).
Methods: A systematic review was conducted. Searches were performed in Medline/PubMed, EMBASE and Virtual Health Library databases, with no restrictions imposed regarding language or year of publication.
Pest Manag Sci
January 2025
College of Plant Protection, Hunan Agricultural University, Changsha, China.
Background: The whitefly Bemisia tabaci is a notorious agricultural pest known for its ability to cause significant crop damage through direct feeding and virus transmission. Its remarkable adaptability and reproductive capacity are linked to its ability to acquire and integrate horizontally transferred genes (HTGs) into its genome. These HTGs increase the physiological and metabolic capacities of this pest, including cholesterol synthesis, which is critical for its survival and reproductive success.
View Article and Find Full Text PDFClin Transl Sci
January 2025
Clinical Pharmacology, Translational Medicine and Clinical Pharmacology, Boehringer-Ingelheim Pharma, Ingelheim, Germany.
Hepatic impairment (HI) trials are traditionally part of the clinical pharmacology development to assess the need for dose adaptation in people with impaired metabolic capacity due to their diseased liver. This review aimed at looking into the data from dedicated HI studies, cluster these data into various categories and connect the effect by HI with reported pharmacokinetics (PK) properties in order to identify patterns that may allow waiver, extrapolations, or adapted HI study designs. Based on a ratio ≥ 2 or ≤ 0.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, King's Health Partners, London SE1 9RT, UK.
Extracorporeal carbon dioxide removal (ECCOR) is an emerging technique designed to reduce carbon dioxide (CO) levels in venous blood while enabling lung-protective ventilation or alleviating the work of breathing. Unlike high-flow extracorporeal membrane oxygenation (ECMO), ECCOR operates at lower blood flows (0.4-1.
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