Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983567 | PMC |
| http://dx.doi.org/10.1016/j.aprim.2013.04.012 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Semiautomated Segmentation and Analysis of Airway Lumen in Pediatric Patients Using Ultra Short Echo Time MRI.
Acad Radiol
February 2024
Department of Physics, Toronto Metropolitan University, Kerr Hall South Bldg., Room KHS-344, 350 Victoria St., Toronto, ON M5B 2K3, Canada (M.K.). Electronic address:
Rationale And Objectives: Ultra short echo time (UTE) magnetic resonance imaging (MRI) pulse sequences have shown promise for airway assessment, but the feasibility and repeatability in the pediatric lung are unknown. The purpose of this work was to develop a semiautomated UTE MRI airway segmentation pipeline from the trachea-to-tertiary airways in pediatric participants and assess repeatability and lumen diameter correlations to lung function.
Materials And Methods: A total of 29 participants (n = 7 healthy, n = 11 cystic fibrosis, n = 6 asthma, and n = 5 ex-preterm), aged 7-18 years, were imaged using a 3D stack-of-spirals UTE examination at 3 T.
Top studies of 2022 relevant to primary care: From the PEER team.
Can Fam Physician
May 2023
Director of Programs and Practice Support at the CFPC.
Objective: To summarize 10 high-quality medical articles published in 2022 that are relevant to primary care physicians.
Selecting The Evidence: Routine surveillance of tables of contents in relevant medical journals and EvidenceAlerts was conducted by the PEER (Patients, Experience, Evidence, Research) team, a group of primary care health care professionals with an interest in evidence-based medicine. Articles were selected and ranked based on relevance to practice.
Objective assessment of atopic dermatitis (AD) is essential for choosing proper management strategies. This study investigated the performance of convolutional neural networks (CNN) models in grading the severity of AD. Five board-certified dermatologists independently evaluated the severity of 9,192 AD images.
View Article and Find Full Text PDFPulmonary functional MRI: Detecting the structure-function pathologies that drive asthma symptoms and quality of life.
Respirology
February 2022
Robarts Research Institute, Western University, London, Ontario, Canada.
Pulmonary functional MRI (PfMRI) using inhaled hyperpolarized, radiation-free gases (such as He and Xe) provides a way to directly visualize inhaled gas distribution and ventilation defects (or ventilation heterogeneity) in real time with high spatial (~mm ) resolution. Both gases enable quantitative measurement of terminal airway morphology, while Xe uniquely enables imaging the transfer of inhaled gas across the alveolar-capillary tissue barrier to the red blood cells. In patients with asthma, PfMRI abnormalities have been shown to reflect airway smooth muscle dysfunction, airway inflammation and remodelling, luminal occlusions and airway pruning.
View Article and Find Full Text PDFAn enriched environment reduces chronic stress-induced visceral pain through modulating microglial activity in the central nucleus of the amygdala.
Am J Physiol Gastrointest Liver Physiol
February 2022
Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Cognitive behavioral therapy (CBT) improves the quality of life for patients with brain-gut disorders; however, the underlying mechanisms of CBT remain to be explored. Previously, we showed that environmental enrichment (EE), an experimental paradigm that mirrors positive behavioral intervention, ameliorates chronic stress-induced visceral hypersensitivity in a rodent model via mechanisms involving altered activity in the central nucleus of amygdala (CeA). In the present study, we investigated whether microglia-mediated synaptic plasticity in the CeA is a potential mechanism underlying the protective effects of EE against stress-induced visceral hypersensitivity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!