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Subpial hemorrhage: A rare and underrecognized site of intracranial hemorrhage in neonates.
Radiol Case Rep
March 2025
From the Department of Radiology, University of Bourgogne Franche-Comté, CHRU Besançon, 3 boulevard Alexandre Fleming, Besançon 25030, France.
Subpial hemorrhage (SPH) is a rare but significant cause of neonatal seizures and respiratory distress, primarily affecting full-term infants without apparent risk factors. We report the case of a full-term newborn who presented with recurrent episodes of apnea, desaturation, and seizures shortly after birth. MRI revealed an acute hemorrhagic collection in the left temporal region, accompanied by cortical cytotoxic edema.
View Article and Find Full Text PDFNeonatal multimorbidity and the phenotype of premature aging in preterm infants.
Pediatr Res
October 2024
Department of Social and Behavioral Sciences, Harvard TH Chan School of Public Health, Boston, USA.
Multimorbidity is the co-occurrence of multiple chronic health problems, associated with aging, frailty, and poor functioning. Children born preterm experience more multimorbid conditions in early life compared to term-born peers. Though neonatal multimorbidity is linked to poor health-related quality of life, functional outcomes, and peer group participation, gaps in our theoretical understanding and conceptualization remain.
View Article and Find Full Text PDFRed cell transfusion related toxic metals exposure for fetus and newborns: an under-recognized public health concern.
Pediatr Res
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Department of Pediatrics, Tufts University School of Medicine, Boston, MA, US.
Detecting Alpha-1 Antitrypsin Deficiency: Current State, Impediments, Opportunities, and Future Directions.
Ann Am Thorac Soc
September 2024
Cleveland Clinic Foundation, Pulmonary, Allergy andCritical Care, Cleveland, Ohio, United States;
Alpha-1 antitrypsin deficiency (AATD) is an under-recognized condition with only a small minority of affected individuals detected, long delays between initial symptoms and diagnosis, and evidence that affected individuals may see many physicians with suggestive symptoms before an initial diagnosis is made. In the context that failure to detect AATD confers harm and that specific therapy is currently available, there is a clear need for enhanced detection. Impediments to enhanced detection include inadequate knowledge about AATD by physicians caring for at-risk patients, inattention to guidelines which endorse testing, a sense of therapeutic nihilism among some physicians (i.
View Article and Find Full Text PDFLung Ultrasound and Regional Heterogeneity: A Bedside Solution to an Underrecognized Problem?
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Neonatal Research, Murdoch Children's Research Institute, Melbourne, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Australia.
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