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Erlotinib-induced Perioral Lesions Resembling Scleroderma.
Acta Dermatovenerol Croat
November 2024
Constantin A. Dasanu MD, PhD, Lucy Curci Cancer Center, Eisenhower Health, 39000 Bob Hope Dr, Rancho Mirage, CA 92270 , USA;
Erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is currently used in the therapy of several solid malignancies. This agent has been associated with several dermatological side-effects, the most common being papulo-pustular acneiform rash. Herein we describe a unique skin effect in a patient treated with erlotinib for non-small cell lung cancer.
View Article and Find Full Text PDFAn Investigation of the Impact of Expanding High-Deductible Health Plans on Patient Decision for Cochlear Implant Surgery and Postoperative Outcomes.
Otol Neurotol
January 2024
Department of Otolaryngology-Head and Neck Surgery, University of Texas Medical Branch, Galveston, Texas.
Hypothesis: After the expansion of high deductibles, patients will delay cochlear implant (CI) surgery to the end of the year, and the risk of postoperative known risks will increase.
Background: The Affordable Care Act was associated with increased enrollment in high-deductible health plans (HDHPs), which resulted in rising health insurance deductibles. Health insurance plans can cover a patient's cost of healthcare once the deductible is met.
Objective: Computational fluid dynamics (CFD) models can potentially aid in pre-operative planning of transarterial radioactive microparticle injections to treat hepatocellular carcinoma, but these models are computationally very costly. Previously, we introduced the hybrid particle-flow model as a surrogate, less costly modelling approach for the full particle distribution in truncated hepatic arterial trees. We hypothesized that higher cross-sectional particle spread could increase the match between flow and particle distribution.
View Article and Find Full Text PDFImpact of lockdown policies during the COVID-19 outbreak on a trauma center of a tertiary hospital in China.
World J Clin Cases
April 2023
Department of Emergency Medicine, Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, Guangdong Province, China.
Background: Coronavirus disease 2019 (COVID-19) is a major and costly public health emergency.
Aim: To investigate the impact of China's lockdown policies during the COVID-19 outbreak on the level I trauma center of a tertiary comprehensive hospital of Traditional Chinese Medicine.
Methods: All patients admitted to our trauma center during a lockdown in 2020 and the same period in 2019 were enrolled.
A Study of Surgical Accuracy with X-Ray-Based Patient-Specific Instrument (X3DPSI) vs Conventional Instrument in Total Knee Arthroplasty Surgeries.
Indian J Orthop
July 2022
Department of Orthopedics, P. D. Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai, 400016 Maharashtra India.
Introduction: Patient-specific instruments (PSI) have been shown to be a good solution in getting accurate bone cuts in total knee arthroplasty (TKA) in many studies. However, the need for an extra CT/MRI makes the existing PSI method costly and unsafe. X-ray-based PSI can solve these problems, if proven to be accurate.
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