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[Biological changes after axonal stretch and their mechanisms]. | LitMetric

[Biological changes after axonal stretch and their mechanisms].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

Department of Orthopaedics, Chinese PLA General Hospital, Beijing 100853, China; Medical College, Nankai University, Tianjin 300071, China.

Published: October 2013

AI Article Synopsis

  • Research on peripheral nerve injuries, particularly those caused by stretching, aims to enhance treatment outcomes and reduce pain for patients.
  • Recent studies focus on the biological and mechanical changes that occur in stretched axons, highlighting their significance in understanding injury recovery.
  • This article summarizes the latest findings related to structural changes in axons, alterations in cellular membranes, cytoskeleton dynamics, metabolism, and action potentials following axonal stretching.

Article Abstract

Research on peripheral nervous injuries, especially the stretched injuries, is important to improve the clinical effectiveness and alleviate the patients's pain. In recent years, the biological changes and mechanics of stretched axons have been hot topics. This article reviews the recent advances in the morphological changes of axons as well as changes in cellular membrane, cytoskeleton, cellular metabolism, and action potential after axonal stretch.

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Source
http://dx.doi.org/10.3881/j.issn.1000-503X.2013.05.016DOI Listing

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