AI Article Synopsis
- The hydrodehalogenation of aryl iodides with a palladium catalyst in methanol shows a significant primary kinetic isotope effect when using both CD3OD and CH3OD.
- This indicates that the process of deprotonation is crucial in the reaction mechanism.
- The findings highlight the importance of hydrogen atoms in determining reaction rates in this chemical transformation.
Article Abstract
The rate of hydrodehalogenation of aryl iodides with a palladium catalyst in methanol exhibits a strong primary kinetic isotope effect from both CD3OD and CH3OD, suggesting that deprotonation plays a major role in the mechanism.
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| http://dx.doi.org/10.1039/c3cc46271d | DOI Listing |
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