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Genome assembly of wisent (Bison bonasus) uncovers a deletion that likely inactivates the THRSP gene.
Commun Biol
November 2024
Animal Genomics, ETH Zurich, Zurich, Switzerland.
Article Synopsis
- * A deletion in the THRSP gene, related to thyroid hormone response, was found in both wisent and bison genomes but not in other cattle species, suggesting that bison may lack this important protein.
- * The study illustrates how super-pangenomes can help identify genetic variations linked to traits across species, while also highlighting challenges in accurately assembling genomes from species that have experienced population bottlenecks.
Cardiometabolic biomarkers and comorbid metabolic syndrome in schizophrenia: A cross-sectional study of long-term clozapine/olanzapine users.
Asian J Psychiatr
December 2024
Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan. Electronic address:
Objectives: Second-generation antipsychotics (SGAs) are often prescribed for patients with schizophrenia; however, SGAs are associated with the risk of metabolic syndrome (MetS). This study aimed to investigate the clinical and biochemical determinants of SGA-related MetS.
Methods: Patients with schizophrenia, aged between 20 and 65 years, and under clozapine or olanzapine treatment for at least 9 months, were recruited from a mental hospital.
Gene expression in the Longissimus dorsi muscle related to meat quality from tropical hair lambs.
Trop Anim Health Prod
July 2024
Department of Animal Science, State University of Acaraú Valley (UVA), Sobral, CE, 62.040-370, Brazil.
The present study describes the expression of genes in the Longissimus dorsi muscle related to meat quality of hair lambs finished in an Integration Crop-Livestock system. Twenty-eight non-castrated lambs of two breeds, Somalis Brasileira and Santa Inês, at 120 ± 15 days of age, with an average initial live weight of 18 ± 3.1 kg, were kept in a pasture-based finishing system with supplementation.
View Article and Find Full Text PDFThyroid hormone-responsive protein mediates the response of chicken liver to fasting mainly through the cytokine-cytokine receptor interaction pathway.
Br Poult Sci
December 2023
College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
1. The objective of this study was to explore the mediating role of thyroid hormone-responsive protein (THRSP) in the response of chicken liver to fasting.2.
View Article and Find Full Text PDFThrsp Gene and the ADHD Predominantly Inattentive Presentation.
ACS Chem Neurosci
February 2023
Institute for New Drug Development, School of Pharmacy, Jeonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju-si, Jeollabuk-do 54896, Republic of Korea.
There are three presentations of attention-deficit/hyperactivity disorder (ADHD): the predominantly inattention (ADHD-PI), predominantly hyperactive-impulsive (ADHD-HI), and combined (ADHD-C) presentations of ADHD. These may represent distinct childhood-onset neurobehavioral disorders with separate etiologies. ADHD diagnoses are behaviorally based, so investigations into potential etiologies should be founded on behavior.
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