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Sex-specific mechanisms in vascular aging: exploring cellular and molecular pathways in the pathogenesis of age-related cardiovascular and cerebrovascular diseases.
Geroscience
January 2025
Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Aging remains the foremost risk factor for cardiovascular and cerebrovascular diseases, surpassing traditional factors in epidemiological significance. This review elucidates the cellular and molecular mechanisms underlying vascular aging, with an emphasis on sex differences that influence disease progression and clinical outcomes in older adults. We discuss the convergence of aging processes at the macro- and microvascular levels and their contributions to the pathogenesis of vascular diseases.
View Article and Find Full Text PDFDemographic and clinical impact on preoperative BREAST-Q ePROM completion and baseline outcomes in women undergoing breast cancer surgery: a quantitative descriptive study at a Danish university hospital.
BMJ Open
January 2025
Department of Plastic and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.
Objectives: This study aimed to investigate patients' use of electronic Patient-Reported Outcome Measures (ePROMs) and understand the demographic and clinical factors that may be correlated with patient responses to the BREAST-Q at the preoperative stage of breast cancer. The BREAST-Q is a PROM in questionnaire format, developed and validated to assess satisfaction and quality of life for breast surgery patients.The hypothesis tested is that considering disparities in geography, age and education among responders is essential for capturing a diverse patient population in future Patent-Reported Outcome Measures initiatives, examining how these characteristics are associated with Patent-Reported Outcome Measures utilisation and outcomes.
View Article and Find Full Text PDFCorrelates of condom use among school-going Thai adolescents: the critical role of bullying victimizations.
BMC Psychiatry
January 2025
Department of Global Public Health and Primary Care, University of Bergen, Årstadveien 17, Bergen, 5009, Norway.
Background: Adolescents face numerous challenges that influence their sexual behaviors. Among these, bullying victimization is a critical yet understudied factor that may impact engagement in unprotected sex. This study investigated the correlates of condom use among school-going Thai adolescents, with a main focus on bullying victimization.
View Article and Find Full Text PDFAssessing the drivers of sexual behavior among youth and its social determinants in Nepal.
PLoS One
January 2025
Health Research and Social Development Forum (HERD) International, Lalitpur, Nepal.
Introduction: Sexual behavior among youth is a public health concern, particularly in contexts where cultural norms, socio-economic factors, and access to comprehensive sexual education play pivotal roles. This paper aims to examine the determinants of sexual behavior among Nepali youths.
Methods: This study analyzed data from 7,122 individuals aged 15-24 years from the Nepal Demographic and Health Survey (NDHS) 2022, focusing on a nationally representative sample.
ICD-11 posttraumatic stress disorder and complex PTSD: prevalence, predictors, and construct validity in Swiss older adults.
Eur J Psychotraumatol
December 2025
Department of Psychology, University of Zurich, Psychopathology and Clinical Intervention, Zurich, Switzerland.
This study assessed the prevalence rates, construct validity, predictors, and psychosocial factors linked to ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD), as assessed by the (ITQ) in a German-speaking sample of Swiss older adults. Participants were = 1526 older adults aged 65+ ( = 72.34; = 6.
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