In a background of very low incidence of hepatitis A HA in the last decade (annual average of 1.8 cases per 100,000 inhabitants) we describe an outbreak of HA which evolved in Mallorca between May and August 2010, whose main focus was a nursery school where more cases were parents and other young relatives of the children of the institution. Thirty-four cases were defined as outbreak cases. Ten were children of the nursery or their siblings and 22 adults (3 staff members of the nursery and 19 relatives; median age 33 years). The first detected cases were children of the same class. There were 2 adults with haematological complications, though not severe. All children, nursery staff members, parents, and siblings of the cases of the first affected class were immediately offered HA vaccination, but only 43.3% eligible individuals accepted it. None of the cases had been vaccinated. The outbreak spread mostly from asymptomatic children to young adults, showing the changes in HA pattern. That is of great concern as the risk of severe illness rises with age. This incident shows the need to implement new HA vaccination policies in outbreak control. This was later carried out.
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http://dx.doi.org/10.1155/2013/684908 | DOI Listing |
Sci Rep
January 2025
Department of Nephrology, the Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University, (Third Military Medical University), Chongqing, China.
Acute kidney injury (AKI) has become a disease of global concern due to its high morbidity and mortality. This has highlighted the need for renoprotective agents. Astragaloside IV (AS-IV) is a saponin isolated from Astragalus membranaceus with good antioxidant, anti-inflammatory and anti-tumor properties.
View Article and Find Full Text PDFBackground: Interactive electronic devices (IEDs) are ubiquitous in young children's lives. However, research on their impact on learning and development is still limited. The aim of this study was to understand the perspectives of early years practitioners (EYPs) and public health consultants (PHCs) on the use of IEDs in children aged 3-5.
View Article and Find Full Text PDFJ Oral Rehabil
January 2025
Department of Restorative Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Background: Temporomandibular disorder (TMD) is the main chronic pain that affects the face, and it is associated with dietary changes due to pain and dysfunction. However, there is a scarcity of studies on its impact on nutrition and vice versa.
Objectives: To assess and compare the intake of energy and nutrients among chronic TMD myalgia and asymptomatic women and to evaluate data according to dietary reference intakes (DRI) and the World Health Organization (WHO) values.
J Child Lang
January 2025
ELTE-HUN-REN NAP Comparative Ethology research group, Research Centre for Natural Sciences, Institute of Cognitive Neuroscience and Psychology, Budapest, Hungary.
By comparing infant-directed speech to spouse- and dog-directed talk, we aimed to investigate how pitch and utterance length are modulated by speakers considering the speech context and the partner's expected needs and capabilities. We found that mean pitch was modulated in line with the partner's attentional needs, while pitch range and utterance length were modulated according to the partner's expected linguistic competence. In a situation with a nursery rhyme, speakers used the highest pitch and widest pitch range with all partners suggesting that infant-directed context greatly influences these acoustic features.
View Article and Find Full Text PDFJ Dev Orig Health Dis
January 2025
Yale School of Medicine, Yale Child Study Center, New Haven, CT, USA.
Early gut microbiome development may impact brain and behavioral development. Using a nonhuman primate model (), we investigated the association between social environments and the gut microbiome on infant neurodevelopment and cognitive function. Infant rhesus monkeys ( = 33) were either mother-peer-reared (MPR) or nursery-reared (NR).
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