Objective: To evaluate the use of a non-breath held 3D-CT-bronchoscopy in detecting tracheobronchomalacia in infants.
Methods: The study was based on 17 infants who received both bronchoscopy and 3D-CT-bronchoscopy within 1 week at our institution. 3D-CT-bronchoscopy consisted of an axial-enhanced-chest-scan and a 3D-volume-external rendering (VR) image of the airways and was scanned with a consciously sedated non-breath held protocol, using a 64-channel-multidetecter-CT scanner. VR images were classified by two radiologists as normal, luminal narrowing or complete obliteration. All patients were confirmed with bronchoscopy and the sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV) was calculated.
Results: Ten (M:F¼7:3, mean 1 month) out of 17 infants were confirmed of tracheobronchomalacia. The sensitivity was <75% in detecting laryngomalacia, tracheomalacia and bronchomalacia. However, the specificity and NPV were higher than 75% for laryngomalacia, tracheomalacia and bronchomalacia and the PPV was 100% in laryngomalacia and tracheomalacia. False-positive cases included secretion plugging, extrinsic compression and foreign body, which were distinguishable in axial scans. The effective radiation dose was 0.73_0.49mSv.
Conclusion: A volume rendering image of the airways can be used to evaluate tracheobronchomalacia and stenosis in infants. Although, non-breath held MDCT is not recommended for screening airway lesions, narrowing of the larynx, and trachea and patency of the bronchus are reliable findings.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ppul.22931 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Free-breathing Accelerated Cardiac MRI Using Deep Learning: Validation in Children and Young Adults.
Radiology
September 2021
From the Department of Radiology, Stanford University School of Medicine, 725 Welch Rd, Stanford, CA 94305 (E.J.Z., A.K., S.S.V.); Department of Electrical Engineering, Stanford University, Stanford, Calif (C.M.S.); and Global MR Applications and Workflow, GE Healthcare, Menlo Park, Calif (P.L.).
Article Synopsis
- A study was conducted to evaluate a new deep learning reconstruction method for cardiac MRI that allows for accelerated imaging without the need for lengthy breath-holds, compared to traditional techniques.
- The deep learning algorithm was tested on both adults and children, assessing the quality and accuracy of the images produced during these faster scans.
- Results showed that the new method significantly reduced scan times while maintaining acceptable image quality, although the traditional method scored slightly better on some quality measures.
Wheezing in Infancy: An Overview of Recent Literature.
Curr Allergy Asthma Rep
September 2017
Rutgers New Jersey Medical School, The State University of New Jersey, 90 Bergen Street, Newark, NJ, 07103, USA.
Purpose Of Review: Wheezing in infancy is a common presentation with many potential causes. In writing this review, we sought to summarize the newest recommendations and testing available for the more common etiologies of wheezing.
Recent Findings: Regarding the diagnosis of asthma, the modified asthma predictive index has recently been established as a useful predictive tool.
Accelerated ferumoxytol-enhanced 4D multiphase, steady-state imaging with contrast enhancement (MUSIC) cardiovascular MRI: validation in pediatric congenital heart disease.
NMR Biomed
January 2017
Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
The purpose of this work was to validate a parallel imaging (PI) and compressed sensing (CS) combined reconstruction method for a recently proposed 4D non-breath-held, multiphase, steady-state imaging technique (MUSIC) cardiovascular MRI in a cohort of pediatric congenital heart disease patients. We implemented a graphics processing unit accelerated CS-PI combined reconstruction method and applied it in 13 pediatric patients who underwent cardiovascular MRI after ferumoxytol administration. Conventional breath-held contrast-enhanced magnetic resonance angiography (CE-MRA) was first performed during the first pass of ferumoxytol injection, followed by the original MUSIC and the proposed CS-PI MUSIC during the steady-state distribution phase of ferumoxytol.
View Article and Find Full Text PDFTracheobronchomalacia in infants: the use of non-breath held 3D CT bronchoscopy.
Pediatr Pulmonol
October 2014
Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Objective: To evaluate the use of a non-breath held 3D-CT-bronchoscopy in detecting tracheobronchomalacia in infants.
Methods: The study was based on 17 infants who received both bronchoscopy and 3D-CT-bronchoscopy within 1 week at our institution. 3D-CT-bronchoscopy consisted of an axial-enhanced-chest-scan and a 3D-volume-external rendering (VR) image of the airways and was scanned with a consciously sedated non-breath held protocol, using a 64-channel-multidetecter-CT scanner.
The effects of breath-holding on pulmonary regurgitation measured by cardiovascular magnetic resonance velocity mapping.
J Cardiovasc Magn Reson
January 2009
Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Background: Pulmonary regurgitation is a common and clinically important residual lesion after repair of tetralogy of Fallot. Cardiovascular magnetic resonance (CMR) phase contrast velocity mapping is widely used for measurement of pulmonary regurgitant fraction. Breath-hold acquisitions, usually acquired during held expiration, are more convenient than the non-breath-hold approach, but we hypothesized that breath-holding might affect the amount of pulmonary regurgitation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!