Objective: To investigate associations between shiftwork and glomerular filtration rate among white/Hispanic (n = 273) and African American (n = 81) police officers.
Methods: Analysis of variance/analysis of variance was utilized to compare mean values of estimated glomerular filtration rate (eGFR) across shiftwork categories.
Results: Shiftwork was significantly associated with eGFR among white/Hispanic officers only: day (88.6 ± 2.8), afternoon (90.6 ± 2.9), and night shift (83.1 ± 3.1 mL/min/1.73 m); afternoon versus night, P = 0.007. Percentage of hours worked on the night shift was inversely associated with mean levels of eGFR, trend P = 0.001. Body mass index modified the association between shiftwork and eGFR (interaction P = 0.038). Among officers with body mass index 25 kg/m or higher, those who worked the night shift had the lowest mean eGFR (afternoon vs night, P = 0.012; day vs night, P = 0.029).
Conclusions: Night-shift work was associated with decreased kidney function among white/Hispanic officers. Longitudinal studies are warranted among all races.
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http://dx.doi.org/10.1097/JOM.0b013e3182a299c9 | DOI Listing |
Acta Cardiol Sin
January 2025
Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey.
Aims: Contrast-induced nephropathy (CIN) is a condition characterized by rapidly decreasing renal funciton following by the application of contrast material. Precutaneous coronary intervention (PCI) is a life-saving treatment method that should be applied under emergent conditions. Unfortunately, the incidence of CIN after PCI is common.
View Article and Find Full Text PDFExp Ther Med
February 2025
Department of Biochemistry, Faculty of Science, Beni-Suef University, Beni-Suef 62511, Egypt.
Inefficient control of elevated blood sugar levels can lead to certain health complications such as diabetic nephropathy (DN) and cardiovascular disease (CVD). The identification of effective biomarkers for monitoring diabetes was performed in the present study. The present study aimed to investigate the implications of long non-coding RNA megacluster (lnc-MGC), microRNA (miR)-132 and miR-133a, and their correlation with lactate dehydrogenase (LDH) activity and glycated hemoglobin (HbA1C) levels to identify biomarkers for the early diagnosis of diabetes mellitus, induced DN and CVD.
View Article and Find Full Text PDFPediatr Nephrol
January 2025
University of Castilla La Mancha, Albacete, Spain.
Background: Serum creatinine and estimated glomerular filtration rate (GFR) are key indicators of kidney function.
Methods: This descriptive, retrospective study included neonatal patients admitted to a tertiary hospital's neonatal intensive care unit from January 2013 to December 2016. Data on kidney function were collected from birth to 7 days of life.
Appl Biochem Biotechnol
January 2025
School of Life Science and Bioengineering, Jining University, 1 Xingtan Road, Qufu, 273155, Shangdong, China.
Creatinine clearance is used to reflect the glomerular filtration rate to assess kidney function. Creatinine degradation-related enzymes have been used for creatinine detection in clinical medicine. The mixture of spores encapsulating either creatininase or creatinase or sarcosine oxidase could mediate a three-step reaction to produce hydrogen peroxide from creatinine.
View Article and Find Full Text PDFBackground: Obesity is a significant risk factor for chronic kidney disease (CKD), with metabolic bariatric surgery offering potential renal benefits. However, there is limited comparative data on the impact of Roux-en-Y gastric bypass (RYGB) versus laparoscopic sleeve gastrectomy (LSG) on renal function in individuals with obesity without end-stage renal disease (ESRD). The objective of this study was to compare renal function outcomes following RYGB and LSG in patients with obesity, focusing on estimated glomerular filtration rate (eGFR), serum creatinine, albumin-creatinine ratio (ACR), and serum cystatin C.
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