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http://dx.doi.org/10.1093/jac/dkt436 | DOI Listing |
J Antimicrob Chemother
March 2014
PathWest Laboratory Medicine, Perth, Western Australia, Australia.
Neurology
July 2009
Division of Neurology, University of British Columbia, Room 8219, GLDHCC, 2775 Laurel St, Vancouver, BC V5Z 1M9, Canada.
Int J Antimicrob Agents
September 2003
CODA-CERVA-VAR, Groeselenberg 99, B-1180 Ukkel, Brussels, Belgium.
Efflux mechanisms that account for resistance to a variety of antimicrobial agents are commonly found in a wide range of bacteria. Two major groups of efflux systems are known, specific exporters and transporters conferring multidrug resistance (MDR). The MDR systems are able to remove antimicrobials of different classes from the bacterial cell and occasionally play a role in the intrinsic resistance of some bacteria to certain antimicrobials.
View Article and Find Full Text PDFCan J Hosp Pharm
June 1990
University Hospital, Vancouver, British Columbia V6T 2B5.
University Hospital, University of British Columbia (UBC) Site, a 600-bed teaching hospital in Vancouver, British Columbia, adopted several cost containment measures on August 2, 1988 in an attempt to limit the rise in antibiotic expenditures. One cost containment measure involved extending the dosing intervals of cefazolin, clindamycin and metronidazole by a pharmacy-based automatic dosing interval interchange. Cefazolin and clindamycin orders were changed to an every eight-hour dosing schedule, and metronidazole orders to an every 12-hour schedule.
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