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| http://dx.doi.org/10.4103/0019-5049.118533 | DOI Listing |
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Patient-reported outcome trajectories the first 24 months after surgery for cervical spondylotic myelopathy: a Quality Outcomes Database study.
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1Neuroscience Institute, Carolina Neurosurgery & Spine Associates, Carolinas Healthcare System, Charlotte, North Carolina.
Objective: Cervical spondylotic myelopathy (CSM) shows varying levels of improvement after surgical treatment. While some patients improve soon after surgery, others may take months to years to show any signs of improvement. The goal of this study was to evaluate postoperative improvement, patient-reported outcomes, and patient satisfaction up to 2 years after surgical treatment for CSM, which will help optimize the current treatment strategies and effectively manage patient expectations.
View Article and Find Full Text PDFPhylogenomic insights into the taxonomy, ecology, and mating systems of the lorchel family Discinaceae (Pezizales, Ascomycota).
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Department of Ecology and Evolutionary Biology and University of Michigan Herbarium, University of Michigan, Ann Arbor, MI 48109, USA.
Lorchels, also known as false morels (Gyromitra sensu lato), are iconic due to their brain-shaped mushrooms and production of gyromitrin, a deadly mycotoxin. Molecular phylogenetic studies have hitherto failed to resolve deep-branching relationships in the lorchel family, Discinaceae, hampering our ability to settle longstanding taxonomic debates and to reconstruct the evolution of toxin production. We generated 75 draft genomes from cultures and ascomata (some collected as early as 1960), conducted phylogenomic analyses using 1542 single-copy orthologs to infer the early evolutionary history of lorchels, and identified genomic signatures of trophic mode and mating-type loci to better understand lorchel ecology and reproductive biology.
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Epilepsy is a major disease affecting millions of people worldwide. Carbamazepine is on the World Health Organization's list of essential medicines and is one of the most prescribed medicines for treating epilepsy. It has a narrow therapeutic range (4-12 μg/mL).
View Article and Find Full Text PDFAnatomic Approach to Fetal Hydrocephalus.
Radiographics
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From the Departments of Radiology and Imaging Sciences (A.M.G., P.J.W., A.M.K.) and Obstetrics and Gynecology (S.E.D.), University of Utah Health, 30 N Mario Capecchi Dr, Salt Lake City, UT 84112; and University of Utah School of Medicine, Salt Lake City, Utah (J.N.C.).
Hydrocephalus is an imprecise term and refers to the imbalance of brain parenchyma and cerebral spinal fluid in the cranial vault. Ventriculomegaly, or enlargement of the ventricular system, is often the more precise term and is therefore preferred. Appropriate imaging and measurement techniques are critical to detect ventriculomegaly and grade its severity.
View Article and Find Full Text PDFChildren's executive functioning and health behaviors across pediatric life stages and ecological contexts.
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Department of Counseling Psychology and Human Services, Prevention Science Institute, University of Oregon, Eugene, OR, USA.
Executive functioning (EF) has been linked to chronic disease risk in children. Health behaviors are thought to partially explain this association. The current cross-sectional study evaluated specific domains of EF and varied health behaviors in three pediatric life stages.
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