From September 2011 to December 2011, 40 women aged 20-68 years with chronic cystitis were examined. All patients were divided into two groups of 20 people depending on the type of treatment. Control group of patients received monotherapy with fosfomycin (monural), main group of patients--complex therapy with fosfomycin and biologically active supplement uroprofit. The results were evaluated at 1 and 2 months after initiation of therapy. Before and after treatment, all patients were examined, including standard laboratory tests, uroflowmetry, cystometry, and cystoscopy. It was shown that patients in main group have a rapid normalization of clinical manifestations and laboratory parameters, improvement of dynamics of the endoscopic picture. Thus, uroprofit has antibacterial, anti-inflammatory action, contributes to the normalization of urodynamics of the lower urinary tract, reduces the risk of relapses of chronic cystitis and can be recommended as a component of the treatment of acute exacerbations of chronic cystitis, as well as a drug for the prevention of disease in the disease-free interval.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The BMT CTN 1703 phase III trial confirmed that graft-versus-host disease (GVHD) prophylaxis with post-transplantation cyclophosphamide (PTCy), tacrolimus (Tac), and mycophenolate mofetil (MMF) results in superior GVHD-free, relapse-free survival (GRFS) compared with Tac/methotrexate (MTX) prophylaxis. This companion study assesses the effect of these regimens on patient-reported outcomes (PROs). Using the Lee Chronic GVHD Symptom Score and PROMIS subscales (physical function, GI symptoms, social role satisfaction) as primary end points and hemorrhagic cystitis symptoms and Lee subscales as secondary end points, responses from English and Spanish speakers were analyzed at baseline and days 100, 180, and 365 after transplant.
View Article and Find Full Text PDFJoint Terminology Report: Terminology Standardization for Female Bladder Pain Syndrome.
Int Urogynecol J
January 2025
Female bladder pain syndrome (FBPS), previously known as interstitial cystitis/bladder pain syndrome, is a life-altering and morbid condition that occurs primarily in female patients and can be variable in presentation. Given the absence of pathognomonic symptoms and sensitive diagnostic tests, significant symptomatic overlap with numerous other pelvic conditions (such as pelvic floor tension myalgia or endometriosis) occurring in women makes diagnosis of FBPS challenging. The frequent co-occurrence of FBPS with other pain conditions and functional somatic syndromes further complicates diagnosis and management.
View Article and Find Full Text PDFJoint Terminology Report: Terminology Standardization for Female Bladder Pain Syndrome.
Urogynecology (Phila)
January 2025
Female bladder pain syndrome (FBPS), previously known as interstitial cystitis/bladder pain syndrome, is a life-altering and morbid condition that occurs primarily in female patients and can be variable in presentation. Given the absence of pathognomonic symptoms and sensitive diagnostic tests, significant symptomatic overlap with numerous other pelvic conditions (such as pelvic floor tension myalgia or endometriosis) occurring in women makes diagnosis of FBPS challenging. The frequent co-occurrence of FBPS with other pain conditions and functional somatic syndromes further complicates diagnosis and management.
View Article and Find Full Text PDFTherapeutic Potential of Feline Adipose-Derived Stem Cell Exosomes in the Treatment of Feline Idiopathic Cystitis: A Characterization and Functional Analysis of miRNA Content.
Nanotheranostics
January 2025
Department of Translational Medicine, University of Ferrara, 44121, Ferrara, Italy.
Feline Idiopathic Cystitis (FIC), is a chronic lower urinary tract condition in cats analogous to PBS/IC in women, which presents significant treatment challenges due to its idiopathic nature. Recent advancements in regenerative medicine highlight the potential of Adipose Tissue-Derived Stem Cells (ADSCs), particularly through their secretome, which includes mediators, bioactive molecules, and extracellular vesicles (EVs). Notably, exosomes, a subset of EVs, facilitate cell-to-cell communication and, when derived from ADSCs, exhibit anti-inflammatory properties and contribute to tissue regeneration.
View Article and Find Full Text PDFClinical Outcomes of Acute Pyelonephritis in Type 2 Diabetes Mellitus.
Cureus
November 2024
Nephrology, Stanley Medical College, Chennai, IND.
Background Diabetes mellitus (DM) is a prevalent predisposing factor for urinary tract infections (UTIs). Among hospitalized patients with acute pyelonephritis, UTIs are more common, severe, and associated with worse outcomes, particularly in those with type 2 DM. Pyelonephritis in DM patients is more frequently bilateral and linked to greater complications, with 90% of emphysematous pyelonephritis (EMPN) and cystitis cases occurring in diabetic individuals.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!