Objective: To investigate the optimal control strategy for Plasmodium vivax malaria transmission in Korea.
Methods: A Plasmodium vivax malaria transmission model with optimal control terms using a deterministic system of differential equations is presented, and analyzed mathematically and numerically.
Results: If the cost of reducing the reproduction rate of the mosquito population is more than that of prevention measures to minimize mosquito-human contacts, the control of mosquito-human contacts needs to be taken for a longer time, comparing the other situations. More knowledge about the actual effectiveness and costs of control intervention measures would give more realistic control strategies.
Conclusion: Mathematical model and numerical simulations suggest that the use of mosquito-reduction strategies is more effective than personal protection in some cases but not always.
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| http://dx.doi.org/10.1016/j.phrp.2012.07.005 | DOI Listing |
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