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The effect of combined low-level nd: YAG laser with mesenchymal stem cells in the healing of diabetic wounds: an experimental study.
Arch Dermatol Res
January 2025
Department of Biomedical Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Although the role of low-level laser therapy (LLLT) and human adipose-derived stem cells (hADSC) in accelerating diabetic wound healing has been proven, their synergistic effect is still debated. This study aimed to evaluate the individual and combined effects of LLLT and hADSC on wound healing and on biomechanical parameters in type 2 diabetic rabbits. In this experimental study, 40 rabbits with type 2 diabetes (induced by streptozotocin (STZ)) were included.
View Article and Find Full Text PDFComparing Sectional and Total Dentin Bond Strengths of Three Endodontic Sealers after Using the Single-cone Obturation Technique: An Study.
J Contemp Dent Pract
October 2024
College of Dentistry, Ajman University, Ajman P.O. Box 346, United Arab Emirates; Department of Endodontic, Faculty of Dentistry, Mansoura University, Egypt, Orcid: https://orcid.org/0000-0003-3391-5306.
Aim: This study aimed to investigate and compare the total and sectional bond strengths of three endodontic sealers when used with the single-cone obturation technique.
Materials And Methods: Forty-five human maxillary central incisors were prepared and divided into three groups according to the type of endodontic sealer: Group I (Gutta-percha/AH Plus Jet), group II (Gutta-percha/GuttaFlow 2), and group III (RealSeal/RealSeal SE). All canals were filled with the single-cone technique.
Effect of Mushroom, Ozone Gas, and Their Combination as Pretreatment Materials on the Bond Strength of Resin Composite to Dentin.
J Contemp Dent Pract
October 2024
Department of Dental Biomaterials, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt, Orcid: https://orcid.org/0000-0002-3420-4146.
Aim: To assess the effect of mushrooms, ozone gas, and their combination as cavity disinfectants on the bonding strength of composite to dentin.
Materials And Methods: The study was conducted on 40 sound premolar teeth randomly divided into four groups. Group I: control group, Group II: mushroom group, Group III: Ozone group, and Group IV: mushroom + ozone gas (combination) group.
Modeling Heart Failure With Preserved Ejection Fraction Using Human Induced Pluripotent Stem Cell-Derived Cardiac Organoids.
Circ Heart Fail
January 2025
Bruce Rapport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (I.R.H., N.K., C.B., O.C.).
Background: The therapeutic armamentarium for heart failure with preserved ejection fraction (HFpEF) remains notably constrained. A factor contributing to this problem could be the scarcity of in vitro models for HFpEF, which hinders progress in developing new therapeutic strategies. Here, we aimed at developing a novel, comorbidity-inspired, human, in vitro model for HFpEF.
View Article and Find Full Text PDFGinsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy.
J Ginseng Res
January 2025
The Key Laboratory of Cardiovascular and Cerebrovascular Drug Research of Liaoning Province, Jinzhou Medical University, Jinzhou, China.
Background: Vascular endothelial dysfunction (VED) is one of the main pathogenic events in pulmonary arterial hypertension (PAH). Previous studies have demonstrated that the ginsenoside Rg1 (Rg1) can ameliorate PAH, but the mechanism by which Rg1 affects pulmonary VED in hypoxia-induced PAH remains unclear.
Methods: Network pharmacology, molecular docking and other experiments were used to explore the mechanisms by which Rg1 affects PAH.
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