Rhabdomyosarcoma (RMS) of the breast is rare and there is scant information about the clinical behavior and treatment strategies. We report an adolescent female patient with metastatic RMS of the breast from the anus. An 18-year-old female patient was referred to our clinic due to palpable mass in the left breast. At age seven, she was diagnosed with acute lymphoblastic leukemia and treated with chemoradiation therapy. After 10 years of complete remission state, she presented with anal mass which was diagnosed as RMS and she received chemoradiation therapy. After 1 year of complete remission state, she noticed a palpable mass in her left breast. The breast mass was diagnosed as metastatic RMS based on core needle biopsy specimen. The RMS in breast was excised for the decreasing tumor burden despite of another metastatic lesion. Although rarely reported, metastasis of RMS should be considered as a cause of breast mass. Tissue biopsy is recommended when clinically suspected lesion is detected.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800733PMC
http://dx.doi.org/10.4048/jbc.2013.16.3.345DOI Listing

Publication Analysis

Top Keywords

rms breast
12
breast
8
adolescent female
8
female patient
8
metastatic rms
8
palpable mass
8
mass left
8
left breast
8
chemoradiation therapy
8
complete remission
8

Similar Publications

extracts are well known for their wide range of nutritional and medicinal benefits, including anti-diabetic, anti-inflammatory, antioxidant, and anti-cancerous properties. Yet, its efficacy against breast cancer has not been well-studied so far. Hence this study aims to investigate the anti-cancer properties of phytochemicals from the bark extract of the tree against BBOX1, a protein that stimulates the growth of Triple Negative Breast Cancer (TNBC) cells.

View Article and Find Full Text PDF

To eliminate vertical HIV transmission and achieve therapy-free viral suppression among children living with HIV, novel strategies beyond antiretroviral therapy (ART) are necessary. Our group previously identified a triple broadly neutralizing antibody (bNAb) combination comprising of 3BNC117, PGDM1400 and PGT151 that mediates robust in vitro neutralization and non-neutralizing effector functions against a cross-clade panel of simian human immunodeficiency viruses (SHIVs). In this study, we evaluated the safety, pharmacokinetics, and antiviral potency of this bNAb combination in infant rhesus macaques (RMs).

View Article and Find Full Text PDF

The Other Site of Rhabdomyosarcoma.

Cancer Med

October 2024

Department of Pediatric Hematology and Oncology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Background: Rhabdomyosarcoma (RMS) is a rare malignant soft tissue sarcoma (STS), accounting for almost 50% of pediatric STSs. Due to its heterogeneity, RMS presents challenges in diagnosis and treatment, with prognosis varying depending on multiple factors. Tumors localized in the other site (OTH)-including the paraspinal, perianal, thoracic, abdominal, pelvic, and perineal regions-are generally classified as unfavorable.

View Article and Find Full Text PDF
Article Synopsis
  • Invasive breast cancer, particularly the no special type subtype, is the most common breast cancer, while lymphoma and melanoma are the primary tumors that spread to the breast.
  • Rhabdomyosarcoma (RMS) is a common pediatric soft-tissue cancer, rare in the breast, typically affecting adolescent girls and mostly presenting as the alveolar variant.
  • A case study of a 17-year-old girl highlights the unusual occurrence of RMS metastasizing to both breasts, initially misdiagnosed as tuberculosis affecting the spine, illustrating the difficulty in diagnosing such rare cases.
View Article and Find Full Text PDF

Naples Prognostic Score: A Novel Predictor of Survival in Patients with Triple-Negative Breast Cancer.

J Inflamm Res

August 2024

The Affiliated Lihuili Hospital, Ningbo University, Ningbo, 315000, People's Republic of China.

Purpose: This study investigated the correlation between the Naples prognostic score (NPS), clinicopathological traits, and the postoperative prognoses of patients with triple-negative breast cancer (TNBC). Based on NPS, a predictive nomogram was developed to estimate the long-term survival probabilities of patients with TNBC post-surgery.

Patients And Methods: We retrospectively examined the clinical records of 223 women with TNBC treated at Ningbo Medical Center, Lihuili Hospital between January 1, 2016 and December 31, 2020.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!