Background: Youth exposed to extreme adverse life conditions have blunted cortisol responses to stress.
Purpose: This study aims to examine whether growing up in highly stigmatizing environments similarly shapes stigmatized individuals' physiological responses to identity-related stress.
Methods: We recruited 74 lesbian, gay, and bisexual young adults (mean age = 23.68) from 24 states with varying levels of structural stigma surrounding homosexuality. State-level structural stigma was coded based on several dimensions, including policies that exclude sexual minorities from social institutions (e.g., same-sex marriage). Participants were exposed to a laboratory stressor, the Trier Social Stress Test (TSST), and neuroendocrine measures were collected.
Results: Lesbian, gay, and bisexual young adults who were raised in highly stigmatizing environments as adolescents evidenced a blunted cortisol response following the TSST compared to those from low-stigma environments.
Conclusions: The stress of growing up in environments that target gays and lesbians for social exclusion may exert biological effects that are similar to traumatic life experiences.
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http://dx.doi.org/10.1007/s12160-013-9556-9 | DOI Listing |
BMC Health Serv Res
January 2025
Makerere University School of Public Health/New Mulago Hospital Complex, P.O. Box 7072, Kampala, Uganda.
Background: Retesting for HIV during pregnancy, labor, and postpartum is crucial for identifying new infections and ensuring timely interventions to prevent mother-to-child transmission (PMTCT). Uganda's national guidelines recommend that pregnant women be retested in the 3rd trimester or during labor/delivery. However, limited information exists regarding adherence to these guidelines, which may affect the effectiveness of PMTCT efforts.
View Article and Find Full Text PDFJ Subst Use Addict Treat
January 2025
University of Pennsylvania School of Nursing, Philadelphia, PA, USA.
Introduction: Community-based overdose prevention sites (OPS) are recognized for reducing overdose deaths and the spread of HIV and hepatitis C among people who use drugs (PWUD). While some hospitals in Europe and Canada have successfully integrated OPS into their facilities, such integration remains illegal in the United States. This study explores the feasibility and acceptability of implementing an OPS at the Hospital of the University of Pennsylvania (HUP), situated in an urban area with high rates of overdose.
View Article and Find Full Text PDFAnnu Rev Clin Psychol
January 2025
2School of Healthcare Leadership, MGH Institute of Health Professions, Boston, Massachusetts, USA.
Researchers, interventionists, and clinicians are increasingly recognizing the importance of structural stigma in elevating the risk of mental illnesses (MIs) and substance use disorders (SUDs) and in undermining MI/SUD treatment and recovery. Yet, the pathways through which structural stigma influences MI/SUD-related outcomes remain unclear. In this review, we aim to address this gap by summarizing scholarship on structural MI/SUD stigma and identifying pathways whereby structural stigma affects MI/SUD-related outcomes.
View Article and Find Full Text PDFPLoS One
January 2025
School of Natural Sciences, Macquarie University, Macquarie Park, Sydney, Australia.
Saffron (Crocus sativus L.) has held significant cultural and medicinal value since the Greek-Minoan civilization. As a triploid spice with vegetative propagation from the Iridaceae family, the three-branch style of C.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Importance: Women who use heroin in sub-Saharan Africa face elevated HIV risk linked to structural vulnerability including frequent incarceration. However, little is known about the association between incarceration and drug use and HIV outcomes among women who use heroin in Africa.
Objective: To estimate associations between incarceration and adverse HIV-related and drug use-related outcomes among women who used heroin.
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