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Primary Intracranial Sarcoma, DICER1-Mutant, With Prominent Chondroid Differentiation: Case Report and Summary of Reported Patients in Literature.
Int J Surg Pathol
January 2025
Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Primary intracranial sarcoma, -mutant, included as a new diagnostic entity in the 2021 WHO Classification of Central Nervous System Tumors, is a rare, but aggressive neoplasm generally identified in the supratentorial forebrain. The prognostic implications of these uncommon tumors and optimal treatment strategy remain unclear. A 19-year-old woman was found unresponsive after reporting a severe headache.
View Article and Find Full Text PDFPrimary Intraosseous Solitary Fibrous Tumor of the Mandible: Report of a Diagnostically Challenging Case with NAB2::STAT6 Fusion and Review of the Literature.
Head Neck Pathol
December 2024
Division of Oral and Maxillofacial Pathology, The Ohio State University, College of Dentistry, 305 W. 12th Ave, Columbus, OH, 43210, USA.
Introduction: Solitary fibrous tumor (SFT) represents an uncommon mesenchymal neoplasm affecting primarily the extremities and deep soft tissues with, overall, benign but locally aggressive biologic behavior and an underlying pathognomonic NAB2::STAT6 fusion. Intraosseous SFTs are infrequent, and involvement of the jawbones is exceedingly rare.
Case Presentation: A 54-year-old woman presented with an asymptomatic, well-demarcated, multilocular radiolucency of the left posterior mandible featuring focally irregular borders, root resorption and lingual cortex perforation.
Life-Threatening Bleeding in Atypical Pleomorphic Adenoma of the Soft Palate.
Iran J Otorhinolaryngol
September 2024
Division of Otorhinolaryngology, Department of Surgical Sciences, University of Turin, Via Genova 3, Turin, Italy.
Introduction: Atypical pleomorphic adenoma (PA) is an uncommon tumor, more frequent in submandibular and parotid glands. PA is classified as atypical when it presents hypercellularity, necrosis or hyalinization, dysplasia, capsular violation or distant metastases.
Case Report: We described a case of a 39-year-old female presented with a slowly growing mass involving the soft palate.
Comprehensive study of ancient schwannoma: Exploring histomorphological diversity and diagnostic challenges.
Rare Tumors
September 2024
Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, India.
Article Synopsis
- * A study analyzed 248 schwannoma cases over six years, with 25 identified as ancient schwannoma, evaluating their histological features through light microscopy.
- * The findings revealed significant features like nuclear atypia and cystic changes in tumors from various locations, highlighting the need for careful histomorphological assessment to correctly diagnose and manage these tumors.
Dermatofibrosarcoma Protuberans in a 12-Year-Old Child: A Rare Case.
Clin Cosmet Investig Dermatol
August 2024
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.
Article Synopsis
- Dermatofibrosarcoma protuberans (DFSP) is a rare skin tumor that typically appears as a firm, slowly growing plaque, mostly found in the trunk area and is uncommon in children.
- A 12-year-old girl showed symptoms of DFSP with a painless dark patch on her nose after radiotherapy; she underwent wide local excision resulting in the removal of the tumor.
- Histopathological examination confirmed the diagnosis as stage II DFSP, and treatment included 25 sessions of radiotherapy, with no recurrence observed after subsequent surgeries.
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