Highly enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic trifluoromethyl ketimines: synthesis of β-amino esters and anti-HIV drug DPC 083.

Hai-Na Yuan Shen Li Jing Nie Yan Zheng Jun-An Ma

Chemistry

Department of Chemistry, Key Laboratory of Systems, Bioengineering (The Ministry of Education), State Synergetic, Innovation Center of Chemical Science and Engineering, Tianjin University, Tianjin 300072 (P. R. of China), Fax: (+86) 22-2740-3475.

Published: November 2013

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http://dx.doi.org/10.1002/chem.201303307	DOI Listing

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