To evaluate the relationship between pregnancy weight gain and placental abruption, Missouri's population-based, maternally linked, longitudinal dataset (1989-2005, n = 1,146,935) was assessed. Regardless of baseline body mass index, women who gained less than the optimal amount recommended by the Institute of Medicine had a 67% increased likelihood of placental abruption (adjusted odds ratio [AOR] for placental abruption = 1.673; 95%CI = 1.588-1.762) compared with those who gained an optimal amount of weight, while those who gained more than the recommended optimal amount of weight had a 30% reduced AOR for placental abruption (AOR = 0.695, 95%CI = 0.660-0.731). These findings underscore the importance of maternal weight management as part of preconception care to improve pregnancy outcomes.
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http://dx.doi.org/10.1111/nure.12063 | DOI Listing |
Front Glob Womens Health
February 2025
Department of Obstetrics and Gynecology, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Objective: To explore the influencing factors of vaginal delivery after cesarean section, establish a predictive model, and identify potential factors for perinatal complications.
Materials And Methods: This is a retrospective analysis of women who attempted a trial of labor after cesarean section(TOLAC) at the Third Affiliated Hospital of Guangzhou Medical University and subsequently gave birth in this hospital between 31 December 31 2017 and December 2023. Associations between maternal characteristics and success of TOLAC were assessed using univariate and logistic regression.
BMC Pregnancy Childbirth
March 2025
Perinatology Department, University of Health Sciences Etlik Zübeyde Hanım Women's Health Care, Training and Research Hospital, Ankara, Turkey.
Objective: The aim of this study was to investigate the relationship between placental abruption and maternal plasma calprotectin levels.
Materials And Methods: This prospective study included 3865 pregnant women aged 24 weeks' gestation and older who were admitted to Etlik Zübeyde Hanım Women's Health Training and Research Hospital between January 2021 and January 2024. Calprotectin levels were prospectively studied in 33 pregnant women with placental abruption and compared with 48 healthy pregnant women matched for age, parity, body mass index (BMI) and week of gestation.
BMJ Open
March 2025
Department of Obstetrics and Gynaecology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Objectives: This study aimed to investigate the association and population-attributable fraction (PAF) of maternal smoking and secondhand smoke (SHS) exposure during pregnancy with placental abruption.
Design: Prospective cohort study.
Setting: 15 regional centres in Japan.
Int J Gynaecol Obstet
March 2025
Department of Embryology, Faculty of Medicine, University of Thessaly, Larissa, Greece.
Pre-eclampsia, placental abruption, and fetal growth restriction (FGR) are collectively referred to as placental ischemic disease (PID). Heat shock proteins (HSPs), originally considered as a response to the heat shock, have a central role in regulating the cellular functions by quality controlling the newly synthesized proteins. The aim of the present review is to investigate the expression of the HSPs in PID and their potential role as biomarkers, based on the available data in the literature.
View Article and Find Full Text PDFEpidemiology
February 2025
Division of Epidemiology and Biostatistics, Department of Obstetrics, Gynecology, and Reproductive Sciences, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.
Background: Mediation analyses of the pre-eclampsia-perinatal outcome association through preterm birth (PTB) have produced paradoxical findings. For example, pre-eclamptic births at preterm gestations show a lower risk of adverse outcomes than normotensive births. These results have been explained by unmeasured baseline confounding between PTB and outcomes, with PTB as the sole mediator.
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