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[Prognosis assessment of alcoholic liver disease: how and why?]. | LitMetric

[Prognosis assessment of alcoholic liver disease: how and why?].

Presse Med

Hôpital Cochin, AP-HP, unité d'hépatologie et d'addictologie, 75014 Paris, France; Inserm U1016, université Paris Descartes, 75014 Paris, France.

Published: February 2014

AI Article Synopsis

Article Abstract

Alcoholic liver disease (ALD) causes more than 5000 deaths per year in France. Most of those deaths could be prevented by an early diagnosis, which would give the patients the opportunity to modify their alcohol consumption while liver lesions are still reversible. Hepatic histology is the main parameter that predicts morbidity and mortality in patients with ALD. Non-invasive methods such as biomarker tests (e.g. FibroTest(®) or FibroMetre A(®)) or hepatic elastography (FibroScan(®)) may allow diagnosing alcohol-induced liver lesion without systematic biopsy. Despite promising preliminary results, those methods are not validated yet in ALD. A validation of non-invasive methods for ALD could allow a large screening of the severe forms of this pathology.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lpm.2013.04.016DOI Listing

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