AI Article Synopsis
- The study analyzed 296 patients with tubo-ovarian abscess (TOA) to evaluate clinical parameters and treatment outcomes.
- About 25.7% of patients required surgery due to ineffective antibiotic treatment, which was linked to larger abscess size and higher levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).
- The findings suggest that integrating sonographic measurements of TOA size with laboratory results (ESR and CRP) can enhance clinical decision-making and predict treatment success.
Article Abstract
Objective: To investigate the clinical and laboratory parameters, treatments, and complications of patient with tubo-ovarian abscess (TOA).
Methods: Data for 296 patients diagnosed with TOA (clinically and sonographically) between January 2005 and December 2012 were retrospectively reviewed at 3 tertiary referral hospitals in Turkey. Patients were compared on the basis of TOA size, demographic characteristics, clinical and sonographic presentation, and laboratory findings.
Results: Seventy-six patients (25.7%) underwent surgery because antibiotic treatment was unsuccessful. The mean abscess size was larger and the mean C-reactive protein (CRP) level and the erythrocyte sedimentation rate (ESR) were higher among patients who required surgery. The ESR had a diagnostic value of 83.6%, and a specificity and sensitivity of 73.7% and 82.7%, respectively, for the need for surgical intervention, based on a cut-off value of 63.0mm/hour. The CRP level had a diagnostic value of 80.4%, a specificity of 82.3%, and a sensitivity of 65.8% based on a cut-off value of 21.0mg/L.
Conclusion: The combined use of the sonographic TOA diameter and laboratory parameters (ESR and CRP level) can aid clinical treatment decisions and improve the prediction of the outcome of medical TOA treatment.
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| http://dx.doi.org/10.1016/j.ijgo.2013.07.017 | DOI Listing |
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