AI Article Synopsis
- The study aimed to connect the apparent diffusion coefficient (ADC) values of prostate cancer patients with their Gleason scores (GS).
- A total of 40 patients with varying GS scores underwent an MRI that included diffusion-weighted imaging (DWI), and the ADC values were compared to their GS.
- The results showed significant differences in ADC values across GS groups, with lower ADC values linked to higher GS scores, suggesting that ADC could assist doctors in differentiating between high- and low-grade prostate cancer.
Article Abstract
Objectives: To correlate the apparent diffusion coefficient (ADC) of prostate cancer patients with pathological Gleason scores (GS).
Methods: 40 patients with GS 2 + 3, 3 + 3, 3 + 4, or 4 + 4 were selected. The magnetic resonance imaging (MRI) study was performed adding axial diffusion-weighted imaging (DWI) sequences to the standard MRI protocol. ADC values obtained were correlated with the GS data.
Results: Statistically significant differences of ADC (p < .05) were found among GS groups with a trend of decreasing ADC values with increasing GS.
Conclusions: The ADC values may help clinicians to delineate prostate carcinoma, recognizing its high- or low-grade compartments.
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| http://dx.doi.org/10.3109/07357907.2013.845673 | DOI Listing |
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