AI Article Synopsis
- Malignant renal subcapsular effusions can result from either primary or metastatic kidney cancers, as highlighted in a unique case involving significant effusion and malignant pleural effusion without a known origin.
- The patient experienced disease progression to carcinomatous meningitis during chemotherapy, where initial treatments including docetaxel plus oxaliplatin and gemcitabine plus cisplatin failed to halt the progression.
- A combination of therapies, including intracavity chemotherapy and immunotherapy alongside gefitinib, ultimately improved treatment outcomes and extended the patient's survival time.
Article Abstract
Malignant renal subcapsular effusions commonly arise from primary or metastatic renal neoplasms. The current case report presents a rare case of malignancy with a massive renal subcapsular effusion accompanied by a malignant pleural effusion of an unknown primary site, which underwent progression to carcinomatous meningitis during chemotherapy. The type of adenocarcinoma present was determined by effusion cytology. Intravenous chemotherapy (docetaxel plus oxaliplatin and gemcitabine plus cisplatin) were administered; however, the disease still progressed. Time to progression was 9 months during treatment of gefitinib. Comprehensive therapies, including intracavity chemotherapy, immunotherapy and gefitinib, were shown to be effective and prolonged the patient's survival time.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789076 | PMC |
| http://dx.doi.org/10.3892/ol.2013.1451 | DOI Listing |
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