AI Article Synopsis
- Bacterial infectious diseases arise from complex interactions between pathogen virulence factors and host responses.
- The Host-Pseudomonas and Coxiella Interaction Database (HoPaCI-DB) is a freely accessible resource that compiles detailed information on host-pathogen interactions specifically for Pseudomonas aeruginosa and Coxiella burnetii.
- Featuring 3,585 validated interactions, the database offers organized data and visual representations, making it a valuable tool for researchers in biology and network studies.
Article Abstract
Bacterial infectious diseases are the result of multifactorial processes affected by the interplay between virulence factors and host targets. The host-Pseudomonas and Coxiella interaction database (HoPaCI-DB) is a publicly available manually curated integrative database (http://mips.helmholtz-muenchen.de/HoPaCI/) of host-pathogen interaction data from Pseudomonas aeruginosa and Coxiella burnetii. The resource provides structured information on 3585 experimentally validated interactions between molecules, bioprocesses and cellular structures extracted from the scientific literature. Systematic annotation and interactive graphical representation of disease networks make HoPaCI-DB a versatile knowledge base for biologists and network biology approaches.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965080 | PMC |
| http://dx.doi.org/10.1093/nar/gkt925 | DOI Listing |
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