Objectives: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clones are spreading rapidly among the population in many regions worldwide. Little information is available on CA-MRSA in Mexico. The aim of this study was to identify CA-MRSA strains in the nose and throat of healthy people in a Mexican community.
Methods: A total of 131 MRSA strains from the nose and throat obtained from healthy people in Mexico City were characterized. The genes mecA, lukS-PV/lukF-PV, and ACME-arcA were detected by PCR. Staphylococcal cassette chromosome mec (SCCmec), pulsed-field gel electrophoresis (PFGE), and spa typing were performed.
Results: Bacteria that had a Panton-Valentine leukocidin (PVL)-positive gene and SCCmec type IV or V were designated as CA-MRSA strains. We found that 21.4% of MRSA strains were CA-MRSA and that the percentage of CA-MRSA strains was similar in the nose and the throat. A great diversity of profiles was found in the strains identified by PFGE pattern and spa typing. Only one strain similar to the USA300 genotype was found; this strain carried the ACME-arcA gene.
Conclusions: CA-MRSA strains were detected in the nose and throat of healthy people. We identified a high level of genetic diversity among CA-MRSA strains in healthy people of Mexico City, which were different from the USA and pandemic clone profiles.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijid.2013.08.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Long-term impact of molecular epidemiology shifts of methicillin-resistant on severity and mortality of bloodstream infection.
Emerg Microbes Infect
December 2025
Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
A 2019 nationwide study in Japan revealed the predominant methicillin-resistant Staphylococcus aureus (MRSA) types in bloodstream infections (BSIs) to be sequence type (ST)8-carrying SCC type IV (ST8-MRSA-IV) and clonal complex 1-carrying SCC type IV (CC1-MRSA-IV). However, detailed patient characteristics and how these MRSA types evolve over time remain largely unknown. In this long-term single-center study, MRSA strains isolated from blood cultures at Nagasaki University Hospital from 2012 to 2019 were sequenced and analyzed.
View Article and Find Full Text PDFMolecular Characteristics of Community-Acquired Methicillin-Resistant , Hospital-Acquired MRSA Isolates, and PVL in one of the Indian hospitals.
Indian J Microbiol
December 2024
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012 India.
Unlabelled: Community-acquired methicillin resistant (CA-MRSA) strains are increasingly replacing hospital-acquired MRSA (HA-MRSA) strains in hospitalized patients leading to poor clinical outcomes. Hence, this study aimed to characterize clinical isolates of MRSA (HA-MRSA and CA-MRSA) and to understand their clonal origin. A total of 400 consecutive clinical isolates were collected from the clinical bacteriology lab of a tertiary care hospital.
View Article and Find Full Text PDFClonal distribution and molecular characterization of isolated strains in Chania and Heraklion, Crete.
Med Pharm Rep
October 2024
Department of Microbiology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Aim: This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of infections.
Methods: The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.
Genomic characterization of MRSA recovered from people with cystic fibrosis during two Spanish multicentre studies (2013 and 2021).
JAC Antimicrob Resist
October 2024
Servicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, España.
Background: Chronic bronchopulmonary infection due to MRSA in people with cystic fibrosis (pwCF) has been associated with accelerated decline in lung function, increased hospitalizations and increased mortality.
Material And Methods: We studied microbiological and genomic characteristics of MRSA isolates recovered from pwCF in two Spanish multicentre studies (2013, 2021). Antimicrobial susceptibility was performed.
Oral Species and MRSA Strains in Patients with Orofacial Clefts Undergoing Surgical Rehabilitation Diagnosed by MALDI-TOF MS.
Pathogens
September 2024
Department of Morphology and Pathology & Biotechnology Graduate Program (PPGBiotec), Center for Biological and Health Sciences (CCBS), Federal University of São Carlos (UFSCar), Km 235 Washington Luís Road, São Carlos 13565-905, SP, Brazil.
Article Synopsis
- - The study analyzed the presence and behavior of oral bacteria in 59 patients with orofacial clefts receiving surgical rehabilitation, focusing on factors like age, gender, and surgical history.
- - Salivary samples were collected and tested using traditional microbiological methods and advanced techniques to identify MRSA strains and overall staphylococcal colonization, with 55.9% of patients showing signs of colonization at different points.
- - Factors influencing oral bacterial colonization during treatment included surgical asepsis practices, the potential for new bacterial colonization in treated areas, and the patients' repeat visits to medical facilities, which might elevate MRSA acquisition risk.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!