AI Article Synopsis

  • Thrombolytics, when delivered through an external ventricular drain, can improve outcomes for patients with intraventricular hemorrhage, a condition that typically has a poor prognosis.
  • Normally, the presence of an arteriovenous malformation (AVM) is seen as a reason not to use thrombolytics, but with high mortality rates from current treatments, this perspective may need to change.
  • The authors analyze existing research and share a new patient case to argue for considering thrombolytics as a treatment option for intraventricular hemorrhage caused by AVMs in specific situations.

Article Abstract

The use of thrombolytics delivered through an external ventricular drain has improved outcomes in intraventricular hemorrhage, a disease with a poor prognosis; however, presence of an arteriovenous malformation is generally considered a contraindication to thrombolytic use. Due do the high mortality with the current standard of care, thrombolytics should be considered as an acceptable treatment option despite the presence of an arteriovenous malformation in certain clinical situations. We review the available literature and present an additional patient to make the case for the use of thrombolytics for intraventricular hemorrhage from an arteriovenous malformation.

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Source
http://dx.doi.org/10.1016/j.jocn.2013.04.031DOI Listing

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