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Mapping the differential impact of spontaneous and conversational laughter on brain and mind: an fMRI study in autism.
Cereb Cortex
May 2024
Institute of Cognitive Neuroscience, University College London, London WC1N 3AZ, United Kingdom.
Spontaneous and conversational laughter are important socio-emotional communicative signals. Neuroimaging findings suggest that non-autistic people engage in mentalizing to understand the meaning behind conversational laughter. Autistic people may thus face specific challenges in processing conversational laughter, due to their mentalizing difficulties.
View Article and Find Full Text PDFNitrous oxide abuse direct measurement for diagnosis and follow-up: update on kinetics and impact on metabolic pathways.
Clin Chem Lab Med
November 2024
CHU Lille, Centre de Biologie Pathologie Génétique, Service Hormonologie Métabolisme Nutrition Oncologie, Lille, France.
Recreational use of nitrous oxide (NO) has become a major health issue worldwide, with a high number of clinical events, especially in neurology and cardiology. It is essential to be able to detect and monitor NO abuse to provide effective care and follow-up to these patients. Current recommendations for detecting NO in cases of recreational misuse and consumption markers are lacking.
View Article and Find Full Text PDFAnalysis of communication styles underpinning clinical decision-making in cancer multidisciplinary team meetings.
Front Psychol
May 2023
Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
Introduction: In cancer care, multidisciplinary team (MDT) meetings are the gold standard. While they are trying to maximize productivity on the back of the steadily increasing workload, growing cancer incidence, financial constraints, and staff shortages, concerns have been raised with regards to the quality of team output, as reported by Cancer Research UK in 2017: "". This study aimed to explore systematically some of the dynamics of group interaction and teamwork in MDT meetings.
View Article and Find Full Text PDFLaughter as a paradigm of socio-emotional signal processing in dementia.
Cortex
September 2021
Dementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Laughter is a fundamental communicative signal in our relations with other people and is used to convey a diverse repertoire of social and emotional information. It is therefore potentially a useful probe of impaired socio-emotional signal processing in neurodegenerative diseases. Here we investigated the cognitive and affective processing of laughter in forty-seven patients representing all major syndromes of frontotemporal dementia, a disease spectrum characterised by severe socio-emotional dysfunction (twenty-two with behavioural variant frontotemporal dementia, twelve with semantic variant primary progressive aphasia, thirteen with nonfluent-agrammatic variant primary progressive aphasia), in relation to fifteen patients with typical amnestic Alzheimer's disease and twenty healthy age-matched individuals.
View Article and Find Full Text PDFHistory of Vasospasm Research in Japan: Commemoration of Professor Tomio Ohta.
Acta Neurochir Suppl
October 2019
Kanamaru Neurosurgical Clinic, Iga, Japan.
In the 1960s Professor Setsuro Ebashi, a physiologist from the University of Tokyo, discovered calcium ion plays a pivotal role in muscle contraction for the first time. However, he was confounded by icy neglect of the society of physiologists. The International Conference on Physiology was held in Boston in 1962, and Dr.
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