We compared hemostimulating activity of glycyram and a preparation of D-glucuronic acid on the model of granulocytic hemopoiesis suppressed by 5-fluorouracil. Different mechanisms were shown to underlie activation of hemopoiesis by the above preparations: D-glucuronic acid directly affects hemopoietic cells, while glycyram modulates local mechanisms regulating hemopoiesis.
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http://dx.doi.org/10.1007/s10517-013-2114-4 | DOI Listing |
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