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Purpose: To provide updated guidance regarding neoadjuvant chemotherapy (NACT) and primary cytoreductive surgery (PCS) among patients with stage III-IV epithelial ovarian, fallopian tube, or primary peritoneal cancer (epithelial ovarian cancer [EOC]).
Methods: A multidisciplinary Expert Panel convened and updated the systematic review.
Results: Sixty-one studies form the evidence base.
Family support and prayer are invaluable coping strategies for our recovery: Experiences of persons living with cardiovascular diseases.
PLoS One
January 2025
Department of Public Health Nursing, School of Nursing and Midwifery, University of Cape Coast, Cape Coast, Ghana.
Background: It is estimated that 61% of deaths caused by Cardiovascular Diseases (CVDs) globally are attributed to lifestyle-related risk factors including tobacco use, alcohol abuse, poor diet, and inadequate physical activity. Meanwhile, inadequate knowledge and misperceptions about CVDs are disproportionately increasing the prevalence of CVDs in Africa. Moreover, pre-diagnosis awareness/knowledge about CVDs among patients is essential in shaping the extent and scope of education to be provided by healthcare workers.
View Article and Find Full Text PDFCTCNet: a fine-grained classification network for fluorescence images of circulating tumor cells.
Med Biol Eng Comput
January 2025
Anhui BioX-Vision Biological Technology Co., Ltd, Hefei, 230031, Anhui, China.
The identification and categorization of circulating tumor cells (CTCs) in peripheral blood are imperative for advancing cancer diagnostics and prognostics. The intricacy of various CTCs subtypes, coupled with the difficulty in developing exhaustive datasets, has impeded progress in this specialized domain. To date, no methods have been dedicated exclusively to overcoming the classification challenges of CTCs.
View Article and Find Full Text PDFA comprehensive review of clinical experiences and extracurricular activities for US premedical students applying to osteopathic medical schools.
J Osteopath Med
January 2025
Department of Biomedical Education, California Health Sciences University College of Osteopathic Medicine, Clovis, CA, USA.
Context: The healthcare industry faces a critical shortage of qualified physicians. To address this growing concern, medical schools nationwide are increasing their efforts to recruit and train premedical students to fill this gap. Those efforts include adequately preparing premedical students with the competencies and skills to meet the application requirements and gain acceptance to the medical school of their choosing.
View Article and Find Full Text PDFIncreasing dosing intervals for biologics in atopic dermatitis-why, who, when and how?
J Eur Acad Dermatol Venereol
January 2025
Department of Dermatology, Oregon Health & Science University, Portland, Oregon, USA.
Biologics approved and in development for atopic dermatitis offer life-changing clinical efficacy with a relatively banal long-term safety profile requiring no laboratory monitoring. Biologic therapies also have their drawbacks, including high payor cost and the need to be administered as every other week subcutaneous injections. Addressing these concerns, studies of longer dosing intervals have been performed in the formal clinical trial setting and during real-world clinical care.
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