Removal of ruthenium using a silica gel supported reagent.

Org Lett

Department of Chemistry, University at Buffalo, The State University of New York, Amherst, New York 14260, United States.

Published: November 2013

A solid-supported isocyanide ligand was developed to destroy active metathesis catalysts and to remove ruthenium byproducts from metathesis reactions. This method was able to significantly reduce the concentration of residual ruthenium from the organic products of several alkene and ene-yne metathesis reactions, under a variety of different conditions.

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http://dx.doi.org/10.1021/ol402339eDOI Listing

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