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Clinical patterns of vitiligo in Japan: A descriptive study using the JMDC claims database.
J Dermatol
January 2025
Department of Dermatology, Faculty of Medicine, Yamagata University, Yamagata, Japan.
Vitiligo is a chronic autoimmune disorder that profoundly impacts patients' quality of life. Real-world data on vitiligo in Japan are limited. This descriptive, cross-sectional study used a claims database to evaluate vitiligo prevalence, patient demographics, treatments, and comorbidities in Japanese patients with vitiligo.
View Article and Find Full Text PDFSevere Symptomatic Anemia as a Rare Initial Manifestation of Type 3 Polyglandular Autoimmune Syndrome: A Case Report.
Cureus
December 2024
Division of Internal Medicine, Unidade Local de Saúde de Braga, Braga, PRT.
Autoimmune polyglandular syndrome type 3 (APS-3) is an uncommon condition marked by autoimmune thyroid disease (ATD) linked with other autoimmune issues, excluding Addison's disease. We report a case of a 41-year-old man who was hospitalized due to exhaustion and macrocytic anemia, later diagnosed with APS-3, which included Hashimoto's thyroiditis, pernicious anemia resulting from autoimmune gastritis, and pre-existing vitiligo. Diagnostic results indicated positive intrinsic factor antibodies, a gastric biopsy compatible with gastritis, elevated thyroid peroxidase antibodies, and significant findings from a thyroid ultrasound.
View Article and Find Full Text PDFInvestigating the impact of perceived social stigmatization and social appearance anxiety on quality of life among patients with facial skin diseases.
Arch Dermatol Res
January 2025
National Institute of Psychology, Quaid-i-Azam University, Islamabad, Pakistan.
Background: This study investigates the interplay between perceived social stigmatization, social appearance anxiety, and quality of life in individuals with facial skin diseases. Furthermore, it undertakes the psychological and social impact of visible skin diseases, such as acne, atopic dermatitis, rosacea, enlarged pores, and vitiligo, on individuals' quality of life. These conditions not only cause physical discomfort but also lead to feelings of sadness, anxiety, and low self-esteem.
View Article and Find Full Text PDFSkin Sceneries of Thyroid Disorders and Impact of Thyroid on Different Skin Diseases: A Scoping Review Focused on Pediatric Patients.
Children (Basel)
December 2024
Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Thyroid function plays a seminal role in the growth and development of children, and alterations in signaling pathways which interfere with the biosynthesis, transport, and metabolism of thyroid hormones might impact on the skin of such patients: this review explores the relationship between different thyroid disorders and dermatological manifestations with a particular focus on the pediatric population. Common cutaneous conditions associated with thyroid dysfunction may include chronic urticaria, vitiligo, and alopecia, which can be early harbingers of an underlying endocrine disruption. This review also highlights the growing cognizance of a "thyroid-skin axis", with thyroid hormones influencing many physiologic processes within the skin such as keratinocyte proliferation, hair growth, and epidermal differentiation.
View Article and Find Full Text PDFThe psychosocial impact of pediatric vitiligo, psoriasis, eczema, and alopecia: A systematic review.
Bull Menninger Clin
December 2024
Emergency medicine physician, NYC Health + Hospitals, Department of Emergency Medicine.
This review focuses on chronic pediatric skin conditions-vitiligo, psoriasis, alopecia, and eczema-and their profound psychosocial impact on children and adolescents. Currently, a comprehensive comparative analysis across these conditions is absent, and comparisons between diverse psychosocial measures are lacking. This review aims to bridge that gap through a systematic review analyzing studies from PubMed and Embase up to April 2023 according to PRISMA.
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