AI Article Synopsis
- Environmental and cellular signals influence how dendrites grow and find their targets, but the specific signals from the substrate are not well understood.
- Research by Dong et al. and Salzberg et al. has identified a complex involving three components that helps transmit signals from the substrate.
- This complex is crucial for guiding the development of intricate dendrite patterns in the organism C. elegans.
Article Abstract
Environmental and cellular cues pattern dendritic growth and direct dendrites to their targets. However, little is known about the signals regulating interactions with the surrounding substrate. Dong et al. and Salzberg et al. now identify a tripartite ligand-receptor complex that conveys cues from the substrate necessary for the patterning of complex dendrites in C. elegans.
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| http://dx.doi.org/10.1016/j.cell.2013.09.029 | DOI Listing |
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Article Synopsis
- Environmental and cellular signals influence how dendrites grow and find their targets, but the specific signals from the substrate are not well understood.
- Research by Dong et al. and Salzberg et al. has identified a complex involving three components that helps transmit signals from the substrate.
- This complex is crucial for guiding the development of intricate dendrite patterns in the organism C. elegans.
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