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Acral and periorificial scaly erythematous plaques in a child.
BMJ
November 2024
Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union medical College, Nanjing, China
Article Synopsis
- Acrodermatitis enteropathica is a rare condition marked by dermatitis, hair loss, and diarrhea, often linked to zinc deficiency, which can occur due to poor diet or complications from parenteral nutrition.
- A 5-year-old child who had been on total parenteral nutrition for a month developed symptoms including skin lesions and extremely low zinc levels, which were found after a challenging diagnosis due to other existing health issues.
- After starting zinc supplementation, the child's condition improved rapidly, highlighting the importance of trace elements in parenteral nutrition and the need to consider acrodermatitis enteropathica in similar cases.
Acquired Acrodermatitis Enteropathica in an Infant.
Cutis
November 2022
Ms. Vu and Drs. Becker and Osswald are from the University of Texas Health Science Center at San Antonio. Ms. Vu is from the Long School of Medicine, and Drs. Becker and Osswald are from the Department of Dermatology. Dr. Gillooly is from Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio.
Article Synopsis
- - Acrodermatitis enteropathica (AE) is a disorder affecting zinc metabolism that leads to zinc deficiency, and it can be either congenital (presenting in infants) or acquired (occurring at any age).
- - Symptoms of AE include red, dry, scaly skin lesions that might turn into crusted or pustular forms, often located on specific body areas and accompanied by hair loss and diarrhea.
- - Treatment typically involves oral zinc supplementation at a dose of 3 mg/kg/d to prevent deficiency symptoms and avoid toxicity; a case study highlighted successful treatment of a 3-month-old infant with acquired AE using this method over three weeks.
Acquired Acrodermatitis enteropathica - an unusual cause of vulva ulceration in a post-operative patient: a case report.
Age Ageing
November 2022
Consultant Dermatologist, King's College Hospital London, SE5 9RS.
Article Synopsis
- Acrodermatitis enteropathica (AE) is a rare disorder that can either be inherited from birth or develop later, characterized by symptoms like skin inflammation around the mouth, diarrhea, skin issues on the extremities, and hair loss.
- The report emphasizes the importance of considering AE as a potential diagnosis in older patients who display mucosal infections or ulcers.
- It details the case of a 68-year-old woman with advanced liver disease who, after a fall resulting in a hip fracture, was found to have persistent mucosal ulcers upon hospital admission.
A case of acrodermatitis enteropathica mimicking mutilating palmoplantar keratoderma.
Indian J Dermatol
January 2022
Consultant Dermatologist, Tattva Skin and laser Clinic, Bhubaneswar, Odisha, India.
Acrodermatitis enteropathica (AE) is a rare inherited form of defective zinc absorption usually manifesting as eczematous and erosive dermatitis preferably over periorificial and acral areas which at times mimics various hereditary palmoplantar keratodermas (PPK). We reported a 6-year-old boy who presented with hard plaques over both palm and sole, and periorificial areas, and flexion attitude of digits without any history of diarrhea and prolonged illness. The patient improved dramatically with zinc supplementation including correction of flexion deformities of the fingers.
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