Valproate-induced hyperammonemic encephalopathy is an unusual but serious adverse effect that is usually characterized by the acute onset of impaired consciousness, focal neurological symptoms and increased seizure frequency. It has been reported to occur at therapeutic valproate levels. We report a patient who developed valproate-induced hyperammonemic encephalopathy after a short treatment with valproate and was successfully treated with levocarnitine. We discuss this patient and review the literature regarding the use of levocarnitine in similar patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jocn.2013.04.033 | DOI Listing |
Publication Analysis
Top Keywords
hyperammonemic encephalopathy
12
treated levocarnitine
8
valproate-induced hyperammonemic
8
valproate induced
4
induced hyperammonemic
4
encephalopathy treated
4
levocarnitine valproate-induced
4
encephalopathy unusual
4
unusual serious
4
serious adverse
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!