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Cytomorphological diagnosis of sarcoidosis using EBUS-TBNA in a tuberculosis-endemic region.
Rev Esp Patol
January 2025
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Background: Sarcoidosis, a granulomatous inflammatory disease, exhibits diverse clinical manifestations, often affecting multiple organs. Diagnostic challenges arise due to its similarities with tuberculosis, particularly in high-burden areas. Differentiating between the two relies on clinical judgment, laboratory tests, imaging, and invasive procedures.
View Article and Find Full Text PDFLarge Language Model Approach for Zero-Shot Information Extraction and Clustering of Japanese Radiology Reports: Algorithm Development and Validation.
JMIR Cancer
January 2025
Division of Radiology and Biomedical Engineering, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Background: The application of natural language processing in medicine has increased significantly, including tasks such as information extraction and classification. Natural language processing plays a crucial role in structuring free-form radiology reports, facilitating the interpretation of textual content, and enhancing data utility through clustering techniques. Clustering allows for the identification of similar lesions and disease patterns across a broad dataset, making it useful for aggregating information and discovering new insights in medical imaging.
View Article and Find Full Text PDFTeaching oral and maxillofacial pathology and oral medicine in undergraduate and postgraduate in Latin America.
Med Oral Patol Oral Cir Bucal
January 2025
Health Science Postgraduate Program State University of Montes Claros Campus Universitário Prof. Darcy Ribeiro Av. Prof. Rui Braga, s/n Vila Mauriceia, Postal Code 39401-089 Montes Claros - MG, Brazil
Background: Oral and Maxillofacial Pathology (OP) and Oral Medicine (OM) are specialties in dentistry responsible for diagnosis and management of diseases affecting the oral and maxillofacial regions, and to best of our knowledge no information about teaching of OP and OM in undergraduate and postgraduate courses in Latin America have been described. The aim of the present study was to evaluate dimensions related to the teaching of OP and OM in South America and Mexico.
Material And Methods: A structured questionnaire was elaborated and sent to 10 countries, with a professional in each country responsible for answering it.
The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity.
Cell Rep
January 2025
Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain; Barcelona Supercomputing Center (BSC), Barcelona, Spain. Electronic address:
Tumors are complex ecosystems of interacting cell types. The concept of cancer hallmarks distills this complexity into underlying principles that govern tumor growth. Here, we explore the spatial distribution of cancer hallmarks across 63 primary untreated tumors from 10 cancer types using spatial transcriptomics.
View Article and Find Full Text PDFA panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets.
Discov Oncol
January 2025
Department of Oncology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, Jiangsu, China.
This study aims to investigate the expression of seven cancer testis antigens (MAGE-A1, MAGE-A4, MAGE-A10, MAGE-A11, PRAME, NY-ESO-1 and KK-LC-1) in pan squamous cell carcinoma and their prognostic value, thus assessing the potential of these CTAs as immunotherapeutic targets. The protein expression of these CTAs was evaluated by immunohistochemistry in 60 lung squamous cell carcinoma (LUSC), 62 esophageal squamous cell carcinoma (ESCA) and 62 head and neck squamous cell carcinoma (HNSC). The relationship between CTAs expression and progression-free survival (PFS) was assessed.
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